1,5-二苯基-1H-1,2,3-噻唑合成路线 （共 27 条）
反应条件
((2,6-C6H3Me2)NCH2C6H4P(C6H5)2)Lu(CH2SiMe3)2(tetrahydrofuran) in hexane; toluene
T=20°C; 72 h; Inert atmosphere;
参考文献
Liu, Bo; Cui, Dongmei
Dalton Transactions, 2009 , # 3 p. 550 - 556
反应条件
1: phenylacetylene With ethyl magnesium chloride in tetrahydrofuran
T=50°C; 0.25 h;
2: diazoaminobenzene in tetrahydrofuran
T=50°C; 1 h;
3: bis(trichloromethyl) carbonate in tetrahydrofuran
参考文献
Krasinski, Antoni; Fokin, Valery V.; Sharpless, K. Barry
Organic Letters, 2004 , vol. 6, # 8 p. 1237 - 1240
反应条件
water; ammonium chloride in tetrahydrofuran
参考文献
THE PENN STATE RESEARCH FOUNDATION
Patent: WO2006/130842 A1, 2006 ;
Location in patent: Page/Page column 13-14 ;
反应条件
4-toluenesulfonyl azide; lithium tert-butylate in dichloromethane
T=20°C; regiospecific reaction;
参考文献
Cheng, Guolin; Zeng, Xiaobao; Shen, Jinhai; Wang, Xuesong; Cui, Xiuling
Angewandte Chemie - International Edition, 2013 , vol. 52, # 50 p. 13265 - 13268
Angew. Chem., 2013
反应条件
1: phenylacetylene With ethyl magnesium chloride in tetrahydrofuran
T=50°C; 0.25 h;
2: diazoaminobenzene in tetrahydrofuran
T=50°C; 1 h;
3: C5H8ClN7O in tetrahydrofuran
参考文献
Krasinski, Antoni; Fokin, Valery V.; Sharpless, K. Barry
Organic Letters, 2004 , vol. 6, # 8 p. 1237 - 1240
反应条件
copper(l) iodide; sodium azide; L-proline; sodium hydroxide in dimethyl sulfoxide
T=90°C; 13 h;
参考文献
Dey, Santu; Pathak, Tanmaya
RSC Advances, 2014 , vol. 4, # 18 p. 9275 - 9278
反应条件
1: phenylacetylene With ethyl magnesium chloride in tetrahydrofuran
T=50°C; 0.25 h;
2: diazoaminobenzene in tetrahydrofuran
T=50°C; 1 h;
3: methyl chloroformate in tetrahydrofuran
参考文献
Krasinski, Antoni; Fokin, Valery V.; Sharpless, K. Barry
Organic Letters, 2004 , vol. 6, # 8 p. 1237 - 1240
反应条件
potassium tert-butylate in water; N,N-dimethyl-formamide
T=20°C; 24 h; air; regioselective reaction;
参考文献
Wu, Luyong; Chen, Yuxue; Tang, Mi; Song, Xinming; Chen, Guangying; Song, Xiaoping; Lin, Qiang
Synlett, 2012 , vol. 23, # 10 art. no. ST-2012-W0003-L, p. 1529 - 1533
反应条件
cerium trifluoromethanesulfonate in toluene
T=100°C; chemoselective reaction;
参考文献
Wang, Ying-Chun; Xie, Yu-Yang; Qu, Hong-En; Wang, Heng-Shan; Pan, Ying-Ming; Huang, Fu-Ping
Journal of Organic Chemistry, 2014 , vol. 79, # 10 p. 4463 - 4469
反应条件
1: lithium phenylacetylide With {Y[N(SiMe3)2]2(μ-Cl)(THF)}2 in tetrahydrofuran
T=-78°C; 1 h; Inert atmosphereSchlenk technique;
2: diazoaminobenzene in tetrahydrofuran
参考文献
Hong, Longcheng; Lin, Weijia; Zhang, Fangjun; Liu, Ruiting; Zhou, Xigeng
Chemical Communications, 2013 , vol. 49, # 49 p. 5589 - 5591
