反应条件
1: 1.) Co2(CO)8, 2.) Me3NO / 1.) CH2CL2, r.t., 1 h, 2.) r.t., 2 h 2: 4 N aq. HCl / 6 h / Heating 3: Ambient temperature 4: 98 percent / H2 / 10percent Pd/C / ethyl acetate / 1 h / 760 Torr 5: diisopropylethylamine / CH2Cl2 / 3 h / Ambient temperature 6: 95 percent / Fe(O), Et3N, HMPA / diethyl ether; tetrahydrofuran / 1.) r.t., 10 min, 2.) r.t., 2 h 7: 1.) O3, 2.) Me2S / 1.) CH2Cl2, -78 deg C 9: tetrahydrofuran; hexane 10: 97 percent / CF3COOH / CH2Cl2 / 1 h / Ambient temperature 11: PDC, 4 Angstroem molecular sieves / dimethylformamide / 20 h / Ambient temperature 13: 3 N LiOH / methanol / 1 h / Heating 14: Li, liq. NH3 / tetrahydrofuran / 0.5 h / -78 °C View Scheme
参考文献
Yoo, Sung-eun; Lee, Sang Hee
Journal of Organic Chemistry, 1994 , vol. 59, # 23 p. 6968 - 6972
