2-甲基-4-羰基-2-环己烯-1-羧酸乙酯合成路线 （共 41 条）
参考文献
Hagemann
Chemische Berichte, vol. 26, p. 876
反应条件
tetrafluoroboric acid in ethanol 4 h;
参考文献
Bezborodov, V. S.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 6 p. 1148 - 1152
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 6 p. 1268 - 1273
反应条件
1: 36 percent / 1) NaOEt / ethanol / 1) 20 deg C, 30 min, 2) reflux, 4.5 h 2: 65 percent / hydrogen / 11percent Pd/C / diethyl ether / 24 h / 1520 Torr 3: 85 percent / CrO3, H2SO4 / acetone / 2 h / 0 °C 4: p-TsOH / methanol / 1.5 h / 25 °C 5: 96 percent / LiAlH4 / tetrahydrofuran / 3 h / Heating 6: 95 percent / 6M aq. HCl / tetrahydrofuran / 1 h / 25 °C View Scheme
参考文献
Jones, J. Bryan; Dodds, David R.
Canadian Journal of Chemistry, 1987 , vol. 65, p. 2397 - 2404
反应条件
1: NaH / dimethylformamide 2: KOH / ethanol 3: 94.6 percent / LiAlH4 / diethyl ether 4: 86.3 percent / pyridine / Ambient temperature View Scheme
参考文献
Jursic, Branko S.; Ladika, Mladen; Sunko, Dionis E.
Tetrahedron, 1993 , vol. 49, # 13 p. 2717 - 2728
反应条件
1: NaH / dimethylformamide 2: KOH / ethanol 3: 90.4 percent / LiAlH4 / diethyl ether 4: 85.5 percent / pyridine View Scheme
参考文献
Ladika, Mladen; Jursic, Branko; Sunko, Dionis E.
Tetrahedron, 1987 , vol. 43, # 1 p. 179 - 190
反应条件
2: BF3*Et2O / diethyl ether 3: 1.) Mg / Et2O View Scheme
参考文献
Banik, Bimal K.; Ghosh, Sukumar; Ghatak, U. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 103 - 104
反应条件
1: NaOEt 2: KOH / ethanol / Heating 3: H2 / Pd-C 4: (i) polyphosphoric acid, (ii) Pd-C, (heating) View Scheme
参考文献
Ghatak,U.R. et al.
Tetrahedron, 1968 , vol. 24, p. 1577 - 1593
反应条件
1: diethyl ether / 0 °C 2: thermal or acidocatalyzed dehydration 3: LDA / tetrahydrofuran / -78 °C 4: tetrahydrofuran / -78 deg C to 20 deg C View Scheme
参考文献
Gesson, J.P.; Jacquesy, J.C.; Renoux, B.
Tetrahedron Letters, 1983 , vol. 24, # 27 p. 2757 - 2760
反应条件
trimethylsilyl trifluoromethanesulfonate in ethanol 1) 1 h, 0 deg C 2) 1 h, r.t.;
参考文献
Hirao, Toshikazu; Mori, Makoto; Ohshiro, Yoshiki
Chemistry Letters, 1991 , # 5 p. 783 - 784
反应条件
in benzene T=0°C; 1 h;
参考文献
Giesson; Jacquesy; Renoux
Tetrahedron, 1984 , vol. 40, # 22 p. 4743 - 4750
