2-氯苯并咪唑合成路线

参考文献

Zhu, Jinmei; Wu, Chun-Feng; Li, Xiaobing; Wu, Gui-Sheng; Xie, Shan; Hu, Qian-Nan; Deng, Zixin; Zhu, Michael X.; Luo, Huai-Rong; Hong, Xuechuan
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 14 p. 4218 - 4224

4857-06-12-氯苯并咪唑+

106-47-8对氯苯胺

24752-30-5N-(苯并咪唑-2-基)-4-氯苯胺

参考文献

SANOFI-AVENTIS U.S. LLC; SHAY, John, J., Jr.; CHANDRAMOULI, Sithamalli, V.; LI, XiaoJie; POWERS, Matthew, R.; AYERS, Timothy, A.; HILLEGASS, Andrea
Patent: WO2011/19781 A1, 2011 ;
Location in patent: Page/Page column 9 ;

4857-06-12-氯苯并咪唑+

100-46-9苄胺

27185-21-3(1H-苯并咪唑-2-基)-苄胺

参考文献

Blythin; Kaminski; Domalski; Spitler; Solomon; Conn; Wong; Verbiar; Bober; Chiu
Journal of Medicinal Chemistry, 1986 , vol. 29, # 6 p. 1099 - 1113

4857-06-12-氯苯并咪唑

2851-13-0N,N-二甲基-1H-苯并咪唑-2-胺

参考文献

Kyowa Hakko Kirin Co., Ltd.; YAMAMOTO, Keisuke; TAMURA, Tomohiro; NAKAMURA, Rina; UENO, Kimihisa; HOSOE, Shintaro
Patent: EP2740730 A1, 2014 ;
Location in patent: Page/Page column ;

4857-06-12-氯苯并咪唑+

68-12-2N,N-二甲基甲酰胺

2851-13-0N,N-二甲基-1H-苯并咪唑-2-胺

参考文献

Petersen, Trine P.; Larsen, Anders Foller; Ritzen, Andreas; Ulven, Trond
Journal of Organic Chemistry, 2013 , vol. 78, # 8 p. 4190 - 4195

4857-06-12-氯苯并咪唑+

124-40-3二甲胺

2851-13-0N,N-二甲基-1H-苯并咪唑-2-胺

参考文献

Benassi, Rois; Grandi, Romano; Pagnoni, Ugo M.; Taddei, Ferdinando; Bocelli, Gabriele; Sgarabotto, Paolo
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1985 , p. 1513 - 1522

4857-06-12-氯苯并咪唑+

506-59-2盐酸二甲胺

2851-13-0N,N-二甲基-1H-苯并咪唑-2-胺

参考文献

Efros et al.
Zhurnal Obshchei Khimii, 1953 , vol. 23, p. 1691,1694; engl. Ausg. S. 1779, 1781

4857-06-12-氯苯并咪唑+

459-46-14-氟溴苄

84946-20-31-(4-氟苄基)-2-氯苯并咪唑

参考文献

Martin, Rainer E.; Green, Luke G.; Guba, Wolfgang; Kratochwil, Nicole; Christ, Andreas
Journal of Medicinal Chemistry, 2007 , vol. 50, # 25 p. 6291 - 6294

4857-06-12-氯苯并咪唑+

352-11-44-氟氯苄

84946-20-31-(4-氟苄基)-2-氯苯并咪唑

参考文献

Janssen Pharmaceutica, N.V.
Patent: US4695575 A1, 1987 ;

4857-06-12-氯苯并咪唑

84946-20-31-(4-氟苄基)-2-氯苯并咪唑

参考文献

Parihar, Harish S.; Suryanarayanan, Asha; Ma, Chun; Joshi, Prasad; Venkataraman, Padma; Schulte, Marvin K.; Kirschbaum, Karen S.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 16 p. 2133 - 2136