4'-氨基-4-氰基联苯合成路线 （共 25 条）
反应条件
potassium carbonate; palladium dichloride in PEG400; water T=20°C; Suzuki-Miyaura coupling; 0.25 h; Air atmosphere;
参考文献
Du, Zhengyin; Zhou, Wanwei; Wang, Fen; Wang, Jin-Xian
Tetrahedron, 2011 , vol. 67, # 26 p. 4914 - 4918
反应条件
dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; palladium diacetate in tetrahydrofuran T=25°C; 2 h; Inert atmosphere;
参考文献
Manolikakes, Georg; Munoz Hernandez, Carmen; Schade, Matthias A.; Metzger, Albrecht; Knochel, Paul
Journal of Organic Chemistry, 2008 , vol. 73, # 21 p. 8422 - 8436
参考文献
You; Brezzell; Das; Hooberman; Sinsheimer
Mutation Research - Genetic Toxicology Testing and Biomonitoring of Environmental or Occupational Exposure, 1994 , vol. 320, # 1-2 p. 45 - 58
反应条件
water; sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether 0.5 h; Heating;
参考文献
Hird, Michael; Seed, Alexander J.; Toyne, Kenneth J.
Synlett, 1999 , # 4 p. 438 - 440
反应条件
sodium tetrahydroborate in methanol T=0 - 20°C;
参考文献
Cho, Young Ae; Kim, Dong-Su; Ahn, Hong Ryul; Canturk, Belgin; Molander, Gary A.; Ham, Jungyeob
Organic Letters, 2009 , vol. 11, # 19 p. 4330 - 4333
反应条件
1: titanium tetrachloride 2: hydroxylamine hydrochloride, acetic achydride / pyridine 3: fuming nitric acid 4: 70 percent / stannic chloride, hydrogen hydrochloride, acetic acid View Scheme
参考文献
Lemenovskii; Makarov; Dyadchenko; Bruce; Larkin; Averkiev; Starikova; Antipin
Russian Chemical Bulletin, 2003 , vol. 52, # 3 p. 607 - 615
反应条件
1: fuming nitric acid 2: 70 percent / stannic chloride, hydrogen hydrochloride, acetic acid View Scheme
参考文献
Comeford, Lorrie; Grunwald, Ernest
Journal of Physical Chemistry, 1990 , vol. 94, # 3 p. 1105 - 1110
反应条件
1: 50 percent / fuming nitric acid; glacial acetic acid / 3 h / Heating 2: 63 percent / dimethylformamide / 8 h / Heating 3: 83 percent / sodium hydrogen sulfide monohydrate / methanol; H2O / 6 h / Heating View Scheme
参考文献
Lemenovskii; Makarov; Dyadchenko; Bruce; Larkin; Averkiev; Starikova; Antipin
Russian Chemical Bulletin, 2003 , vol. 52, # 3 p. 607 - 615
反应条件
1: 63 percent / bromine; iron / CHCl3 / 3 h / Heating 2: 63 percent / dimethylformamide / 8 h / Heating 3: 83 percent / sodium hydrogen sulfide monohydrate / methanol; H2O / 6 h / Heating View Scheme
参考文献
Lemenovskii; Makarov; Dyadchenko; Bruce; Larkin; Averkiev; Starikova; Antipin
Russian Chemical Bulletin, 2003 , vol. 52, # 3 p. 607 - 615
反应条件
1: 63 percent / dimethylformamide / 8 h / Heating 2: 83 percent / sodium hydrogen sulfide monohydrate / methanol; H2O / 6 h / Heating View Scheme
参考文献
Lemenovskii; Makarov; Dyadchenko; Bruce; Larkin; Averkiev; Starikova; Antipin
Russian Chemical Bulletin, 2003 , vol. 52, # 3 p. 607 - 615
