2,3-二羟基-1,4-二氧杂环己烷合成路线 （共 16 条）
反应条件
in water; benzene 10 h; Heating;
参考文献
Venuti, Michael C.
Synthesis, 1982 , # 1 p. 61 - 63
参考文献
Raudnitz
Chemistry and Industry (London, United Kingdom), 1956 , p. 166
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Journal of the Chemical Society, 1955 , p. 1036
反应条件
in ethanol 0.5 h; Ambient temperature;
参考文献
Venuti, Michael C.
Synthesis, 1982 , # 1 p. 61 - 63
反应条件
toluene-4-sulfonic acid 1.) ethylene glycol, 100 deg C, 15 min; 2.) ethylene glycol; Multistep reaction;
参考文献
Davies, Alwyn G.; Shields, Charles J.; Evans, Jeffrey C.; Rowlands, Christopher C.
Canadian Journal of Chemistry, 1989 , vol. 67, p. 1748 - 1752
反应条件
in ethanol 0.5 h; Ambient temperature;
参考文献
Synthesis, , # 1 p. 61 - 63
反应条件
in methanol T=20°C; 5 h; Reflux;
参考文献
Ishizuka, Tomoya; Sinks, Louise E.; Song, Kai; Hung, Sheng-Ting; Nayak, Animesh; Clays, Koen; Therien, Michael J.
Journal of the American Chemical Society, 2011 , vol. 133, # 9 p. 2884 - 2896
反应条件
in ethanol T=20°C; 28 h;
参考文献
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT; BAeRFACKER, Lars; KAST, Raimund; GRIEBENOW, Nils; MEIER, Heinrich; KOLKHOF, Peter; ALBRECHT-KUePPER, Barbara; NITSCHE, Adam; STASCH, Johannes-Peter; SCHNEIDER, Dirk; TEUSCH, Nicole; RUDOLPH, Joachim; WHELAN, James; BULLOCK, William; PLEASIC-WILLIAMS, Susan
Patent: WO2010/20363 A1, 2010 ;
Location in patent: Page/Page column 117 ;
参考文献
Venuti, Michael C.
Synthesis, 1982 , # 1 p. 61 - 63
反应条件
1: With acetic acid in tetrahydrofuran; ethanol
T=-78°C; 0.5 h;
2: With triethylamine
T=25°C; 24 h;
参考文献
Akritopoulou-Zanze, Irini; Wang, Ying; Zhao, Hongyu; Djuric, Stevan W.
Tetrahedron Letters, 2009 , vol. 50, # 42 p. 5773 - 5776
反应条件
in ethanol; water
Heating;
参考文献
Torgashev, P. A.; Kazantseva, I. V.; Chupakhin, O. N.; Charushin, V. N.; Belik, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989 , vol. 25, # 8 p. 936 - 943
Khimiya Geterotsiklicheskikh Soedinenii, 1989 , # 8 p. 1118 - 1125
