3-(1-萘基)-2-丙炔酸合成路线 （共 25 条）
反应条件
triethylamine; copper(l) chloride in acetonitrile T=60°C; 2 h; Inert atmosphere;
参考文献
Kolarovic, Andrej; Faberova, Zuzana
Journal of Organic Chemistry, 2009 , vol. 74, # 18 p. 7199 - 7202
反应条件
formaldehyd in acetonitrile T=65°C; 3 h;
参考文献
Park, Kyungho; Heo, Yumi; Lee, Sunwoo
Organic Letters, 2013 , vol. 15, # 13 p. 3322 - 3325
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine in N,N-dimethyl-formamide
T=20°C; Inert atmosphere;
参考文献
Kolarovic, Andrej; Faberova, Zuzana
Journal of Organic Chemistry, 2009 , vol. 74, # 18 p. 7199 - 7202
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=24°C; 20 h;
参考文献
Yu, Dingyi; Tan, Mei Xuan; Zhang, Yugen
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 6 p. 969 - 974
反应条件
tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene in dimethyl sulfoxide
T=35°C; Sonogashira Cross-Coupling; 24 h;
参考文献
Park, Kyungho; You, Jung-Min; Jeon, Seungwon; Lee, Sunwoo
European Journal of Organic Chemistry, 2013 , # 10 p. 1973 - 1978
反应条件
1: With cesium fluoride in dimethyl sulfoxide
T=20°C; 3 h; Schlenk technique;
2: With hydrogenchloride in water
T=0°C; pH=> 1;
参考文献
Yonemoto-Kobayashi, Misato; Inamoto, Kiyofumi; Tanaka, Yoshiyuki; Kondo, Yoshinori
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 23 p. 3773 - 3775
反应条件
water; potassium hydroxide in methanol
T=25°C; 12 h;
参考文献
Hapke, Marko; Kral, Karolin; Spannenberg, Anke
Synthesis, 2011 , # 4 art. no. Z27710SS, p. 642 - 652
反应条件
potassium hydroxide in methanol
0.5 h;
参考文献
Al-Arab, Mohammad M.
Journal of Chemical & Engineering Data, 1985 , vol. 30, # 4 p. 493
反应条件
SPhos; C16H16Cl2N2O4Pd2; N-hexadecyl-N,N,N-trimethylammonium bromide; triethylamine in water
T=130°C; Sonogashira Cross-Coupling; 0.5 h; Microwave irradiation;
参考文献
Civicos, Jose F.; Alonso, Diego A.; Najera, Carmen
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 1 p. 203 - 208
反应条件
alkali hydroxide in 1,4-dioxane; water
T=30°C; ΔH(excit.), ΔS(exit.); KineticsThermodynamic dataRate constant;
参考文献
Bowden, Keith; Hojatti, Mahmood
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1990 , # 7 p. 1197 - 1200
