2-羟基-3-甲基-1,4-萘醌合成路线 （共 82 条）
反应条件
1: oxygen / 1,4-dioxane; water / 6 h / 20 °C
2: H4SiW12O40 / 48 h / 20 °C
3: potassium hydroxide / methanol / 6 h / 20 °C
View Scheme
参考文献
Hadjila, Dokari; Mohamed, Hammadi
Asian Journal of Chemistry, 2013 , vol. 25, # 11 p. 6112 - 6116
反应条件
potassium hydroxide in methanol
1 h; Reflux;
参考文献
Nasiri, Hamid Reza; Madej, M. Gregor; Panisch, Robin; Lafontaine, Michael; Bats, Jan W.; Lancaster, C. Roy D.; Schwalbe, Harald
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9530 - 9541
反应条件
1: (NH4)2S2O8; silver nitrate / acetonitrile; water / 80 °C
2: dihydrogen peroxide; sodium carbonate
View Scheme
参考文献
Nasiri, Hamid Reza; Madej, M. Gregor; Panisch, Robin; Lafontaine, Michael; Bats, Jan W.; Lancaster, C. Roy D.; Schwalbe, Harald
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9530 - 9541
反应条件
1: (NH4)2S2O8; silver nitrate / acetonitrile; water / 80 °C
2: potassium hydroxide / methanol / 1 h / |Reflux
View Scheme
参考文献
Nasiri, Hamid Reza; Madej, M. Gregor; Panisch, Robin; Lafontaine, Michael; Bats, Jan W.; Lancaster, C. Roy D.; Schwalbe, Harald
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9530 - 9541
反应条件
sodium dithionite; potassium tert-butylate; oxygen
1.) benzene, 2 min, 2.) t-BuOH, 5 min.; Yield given. Multistep reaction;
参考文献
Ghera, Eugene; Ben-David, Yoshua
Journal of Organic Chemistry, 1985 , vol. 50, # 18 p. 3355 - 3359
反应条件
in benzene
Ambient temperatureIrradiation;
参考文献
Maruyama, Kazuhiro; Osuka, Atsuhiro; Suzuki, Hitomi
Journal of the Chemical Society, Chemical Communications, 1980 , # 7 p. 323 - 324
反应条件
1: 85 percent / 1.) K2CO3 / 1.) acetone, 45 deg C, 1 h, 2.) acetone, 2 h
View Scheme
参考文献
Wurm, Gotthard; Geres, Uwe
Archiv der Pharmazie (Weinheim, Germany), 1984 , vol. 317, # 7 p. 606 - 609
反应条件
1: diethyl ether; hydrogen chloride / Behandeln des Reaktionsgemisches mit wss. Natronlauge
2: aqueous sulfuric acid
3: sulfuric acid
4: diethyl ether; sodium ethylate
View Scheme
参考文献
Asano; Hase
Yakugaku Zasshi, 1941 , vol. 61, p. 59,60; dtsch. Ref. S. 55
Chem.Abstr., 1942 , p. 2259
反应条件
1: pyridine hydrochloride
2: acetic acid; CHCl3; lead (IV)-acetate
3: aqueous acetic acid
View Scheme
参考文献
Ebnoether et al.
Helvetica Chimica Acta, 1952 , vol. 35, p. 910,926
反应条件
2: LiAlH4; THF
3: pyridine hydrochloride
4: acetic acid; CHCl3; lead (IV)-acetate
5: aqueous acetic acid
View Scheme
参考文献
Ebnoether et al.
Helvetica Chimica Acta, 1952 , vol. 35, p. 910,926
