5,5'-二溴-2,2'-联噻吩合成路线 （共 35 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in water; toluene 24 h; Reflux;
参考文献
LG Chem. Ltd.; Bae, Jae Soon; Lee, Dae Woong; Lee, Dong Hoon; Lee, Jae Chol; Jang, Jun Gi
Patent: US8674138 B2, 2014 ;
Location in patent: Page/Page column 143-144 ;
反应条件
n-butyllithium 1.) THF, 0 deg C, 30 min, 2.) THF, -78 deg C; Yield givenMultistep reaction. Yields of byproduct given;
参考文献
Hughes, Terry V.; Cava, Michael P.
Journal of Organic Chemistry, 1999 , vol. 64, # 1 p. 313 - 315
反应条件
1: 2-bromo-5-(5-bromothiophen-2-yl)thiophene With n-butyllithium in tetrahydrofuran; hexane T=0°C; 2: methyl trifluoromethanesulfonate in tetrahydrofuran; hexane T=0°C;
参考文献
Organic Letters, , vol. 10, # 18 p. 3937 - 3940
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; water Suzuki Coupling; Inert atmosphereReflux;
参考文献
Canesi, Eleonora V.; Fazzi, Daniele; Colella, Letizia; Bertarelli, Chiara; Castiglioni, Chiara
Journal of the American Chemical Society, 2012 , vol. 134, # 46 p. 19070 - 19083
反应条件
lithium diisopropyl amide in tetrahydrofuran
T=-70°C; Inert atmosphere;
参考文献
BASF SE; Kirner, Hans Jürg; Bienewald, Frank; Flores, Jean-Charles; Aebischer, Olivier Frédéric
Patent: US8436208 B2, 2013 ;
Location in patent: Page/Page column 32; 33 ;
