5,5'-二溴-2,2'-联噻吩合成路线 （共 35 条）
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II) in diethyl ether 0.5 h; Heating;
参考文献
Pham, Chiem Van; Burkhardt, A.; Shabana, R.; Cunningham, David D.; Mark, Harry B.; Zimmer, Hans
Phosphorus, Sulfur and Silicon and the Related Elements, 1989 , vol. 46, p. 153 - 168
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium fluoride; potassium hydroxide; aluminum oxide T=80°C; Suzuki coupling; 0.05 h; microwave irradiation;
参考文献
Melucci, Manuela; Barbarella, Giovanna; Sotgiu, Giovanna
Journal of Organic Chemistry, 2002 , vol. 67, # 25 p. 8877 - 8884
反应条件
1: thien-2-yl bromide With magnesium in tetrahydrofuran 3 h; Heating; 2: 2-bromo-5-(5-bromothiophen-2-yl)thiophene With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran Kumada coupling; Heating; Further stages.;
参考文献
Li, Zhong Hui; Wong, Man Shing; Tao, Ye; Fukutani, Hiroshi
Organic Letters, 2007 , vol. 9, # 18 p. 3659 - 3662
反应条件
bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran 20 h; Heating;
参考文献
Kamal, Marwan R.; Al-Taweel, Samir A.; El-Abadelah, Mustafa M.; Ajaj, Khalid M. Abu
Phosphorus, Sulfur and Silicon and the Related Elements, 1997 , vol. 126, p. 65 - 74
反应条件
Suzuki coupling; Inert atmosphere;
参考文献
Fitzner, Roland; Reinold, Egon; Mishra, Amaresh; Mena-Osteritz, Elena; Baeuerle, Peter; Ziehlke, Hannah; Koerner, Christian; Leo, Karl; Riede, Moritz; Weil, Matthias; Tsaryova, Olga; Weiss, Andre; Uhrich, Christian; Pfeiffer, Martin
Advanced Functional Materials, 2011 , vol. 21, # 5 p. 897 - 910
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=0°C; 2: With methanol in tetrahydrofuran; hexane T=0°C;
参考文献
Organic Letters, , vol. 10, # 18 p. 3937 - 3940
反应条件
n-butyllithium in tetrahydrofuran; hexane 1.) -70 deg C, 30 min;
参考文献
Pham, Chiem Van; Burkhardt, A.; Shabana, R.; Cunningham, David D.; Mark, Harry B.; Zimmer, Hans
Phosphorus, Sulfur and Silicon and the Related Elements, 1989 , vol. 46, p. 153 - 168
反应条件
1: 2-bromo-5-(5-bromothiophen-2-yl)thiophene With n-butyllithium in tetrahydrofuran; hexanes T=-78 - 20°C; 2 h; 2: N,N-dimethyl-formamide in tetrahydrofuran; hexanes T=20°C; 2 h;
参考文献
UNIVERSITE LAVAL
Patent: WO2005/16882 A1, 2005 ;
Location in patent: Page/Page column 29 ;
反应条件
1: 92.7 percent / dichlorobis(benzonitrile)palladium(II), PPh3, CuI / various solvent(s) / 4 h / 70 °C 2: 95.8 percent / K2CO3 / methanol / 4 h / Ambient temperature View Scheme
参考文献
Dahlmann, Uwe; Neidlein, Richard
Helvetica Chimica Acta, 1996 , vol. 79, # 3 p. 755 - 766
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in water; toluene 24 h; Heating / reflux;
参考文献
LG CHEM. LTD.
Patent: WO2007/46658 A1, 2007 ;
Location in patent: Page/Page column 35 ;
