2,4,6-三羟基苯乙酮一水合物合成路线 （共 215 条）
反应条件
potassium hydroxide in methanol T=20°C; 24 h;
参考文献
Wang, Xue; Lee, Yong Rok
Tetrahedron, 2011 , vol. 67, # 47 p. 9179 - 9184
反应条件
potassium carbonate in acetone T=74°C; 4 h;
参考文献
Basabe; De Roman; Marcos; Diez; Blanco; Bodero; Mollinedo; Sierra; Urones
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 9 p. 4258 - 4269
反应条件
boron trifluoride diethyl etherate
参考文献
Fujimoto, Tomoko; Nomura, Taro
Heterocycles, 1984 , vol. 22, # 5 p. 997 - 1003
参考文献
Riedl; Huebner
Chemische Berichte, 1957 , vol. 90, p. 2870,2875
参考文献
Boubakir, Zakia; Beuerle, Till; Liu, Benye; Beerhues, Ludger
Phytochemistry, 2005 , vol. 66, # 1 p. 51 - 57
反应条件
1: 92 percent / K2CO3 / acetone / 3 h / 65 °C 2: 60 percent / aluminium chloride / chlorobenzene / 1 h / Heating 3: 99 percent / K2CO3 / acetone / Heating 4: 29 percent / NaOH; K2S2O8; pyridine / H2O / 24 h / 20 °C View Scheme
参考文献
Kavvadias, Dominique; Sand, Philipp; Youdim, Kuresh A.; Qaiser, M. Zeeshan; Rice-Evans, Catherine; Baur, Roland; Sigel, Erwin; Rausch, Wolf-Dieter; Riederer, Peter; Schreier, Peter
British Journal of Pharmacology, 2004 , vol. 142, # 5 p. 811 - 820
反应条件
1: 92 percent / K2CO3 / acetone / 3 h / 65 °C 2: 60 percent / aluminium chloride / chlorobenzene / 1 h / Heating 3: 99 percent / K2CO3 / acetone / Heating 4: 29 percent / NaOH; K2S2O8; pyridine / H2O / 24 h / 20 °C 5: 59 percent / K2CO3 / acetone / Heating View Scheme
参考文献
Kavvadias, Dominique; Sand, Philipp; Youdim, Kuresh A.; Qaiser, M. Zeeshan; Rice-Evans, Catherine; Baur, Roland; Sigel, Erwin; Rausch, Wolf-Dieter; Riederer, Peter; Schreier, Peter
British Journal of Pharmacology, 2004 , vol. 142, # 5 p. 811 - 820
反应条件
1: potassium carbonate / acetone / 5 h / |Reflux 2: sodium hydroxide / ethanol / 0.5 h / 50 °C 3: iodine / dimethyl sulfoxide / 0.5 h / 150 °C / |Inert atmosphere View Scheme
参考文献
Deodhar, Mandar; Wood, Kasey; Black, David Stclair; Kumar, Naresh
Australian Journal of Chemistry, 2012 , vol. 65, # 10 p. 1377 - 1383,7
反应条件
1: 72 percent / NaH / dimethylformamide / 2 h / Ambient temperature 2: 94 percent / sodium hydroxide / ethanol / 4 h 3: 96 percent / 30percent H2O2, 5percent NaOH / methanol / 4 h / Ambient temperature 4: 19 percent / conc. HCl / methanol / 0.25 h / 70 °C View Scheme
参考文献
Tanaka; Hiroo; Ichino; Ito
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 6 p. 1441 - 1445
反应条件
N-hexadecyl-N,N,N-trimethylammonium bromide in sodium hydroxide; chloroform Ambient temperature;
参考文献
Nath, Swadhin; Bhattacharyya, Anjan; Sengupta, P. K.
Journal of the Indian Chemical Society, 1983 , vol. 60, p. 801 - 802
