2,4,6-三羟基苯乙酮一水合物合成路线 （共 215 条）
反应条件
sodium hydroxide; tetra-(n-butyl)ammonium iodide in dichloromethane; water T=20°C; 24 h;
参考文献
Journal of Natural Products, , vol. 71, # 7 p. 1237 - 1241
反应条件
potassium carbonate in acetone 5 h; Heating;
参考文献
Gray, Christopher A.; Kaye, Perry T.; Nchinda, Aloysius T.
Journal of Natural Products, 2003 , vol. 66, # 8 p. 1144 - 1146
反应条件
potassium carbonate in acetone 5 h; Heating;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, p. 57 - 58
反应条件
in methanol; hexane; chloroform T=20°C; Cooling with ice;
参考文献
European Journal of Medicinal Chemistry, , vol. 45, # 9 p. 4258 - 4269
参考文献
Tillekeratne; Sherette, Angela; Fulmer, Jennifer A; Hupe, Lynn; Hupe, Donald; Gabbara, Sam; Peliska, James A; Hudson, Richard A
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 4 p. 525 - 528
参考文献
Sonn; Buelow
Chemische Berichte, 1925 , vol. 58, p. 1697
参考文献
Sastri; Seshadri
Proceedings - Indian Academy of Sciences, Section A, 1946 , vol. 23, p. 262,266
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 20 °C 2: sodium hydride / N,N-dimethyl-formamide / 20 °C 3: iodine / dimethyl sulfoxide / 110 °C 4: 3,3-dimethyldioxirane / dichloromethane; acetone / 0 °C 5: acetic acid / water / 110 °C 6: potassium carbonate / N,N-dimethyl-formamide / 5 h / 20 °C 7: methanol; sodium methylate / 5 h / 20 °C 8: hydrogen; palladium(II) oxide hydrate / tetrahydrofuran; methanol / 6 h / 20 °C View Scheme
参考文献
Yamasaki, Kazuaki; Hishiki, Ryogo; Kato, Eisuke; Kawabata, Jun
ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 1 p. 17 - 21
反应条件
potassium carbonate in water; acetone Inert atmosphereReflux;
参考文献
Chee, Chin Fei; Buckle, Michael J.C.; Rahman, Noorsaadah Abd.
Tetrahedron Letters, 2011 , vol. 52, # 24 p. 3120 - 3123
反应条件
1: 2',4',6'-trihydroxyacetophenone With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 3.25 h; Inert atmosphere; 2: benzoyl chloride in tetrahydrofuran T=-78 - 20°C; 5.16667 h; Inert atmosphere;
参考文献
Li, Su-Yi; Wang, Xiao-Bing; Xie, Sai-Sai; Jiang, Neng; Wang, Kelvin D.G.; Yao, He-Quan; Sun, Hong-Bin; Kong, Ling-Yi
European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 632 - 646
