4-甲氧基-2-苯并呋喃-1(3H)-酮合成路线 （共 48 条）
反应条件
1: 33 percent / acid
2: 71 percent / NaOH
View Scheme
参考文献
Gupta, Dahmendra N.; Hodge, Philip; Hurley, Peter N.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 391 - 394
反应条件
hydrogenchloride
Heating;
参考文献
Meyers, A. I.; Avila, Walter B.
Journal of Organic Chemistry, 1981 , vol. 46, # 19 p. 3881 - 3886
反应条件
1: NBS / benzoyl peroxide / CCl4 / 1 h / Heating; Irradiation
2: 96.4 percent / 6N HCl aq / Heating
View Scheme
参考文献
Meyers, A. I.; Avila, Walter B.
Journal of Organic Chemistry, 1981 , vol. 46, # 19 p. 3881 - 3886
反应条件
2: SOCl2
3: 1.) n-BuLi / 1.) THF, hexane, -45 deg C, 1.5h, 2.) room temp.
4: NBS / benzoyl peroxide / CCl4 / 1 h / Heating; Irradiation
5: 96.4 percent / 6N HCl aq / Heating
View Scheme
参考文献
Meyers, A. I.; Avila, Walter B.
Journal of Organic Chemistry, 1981 , vol. 46, # 19 p. 3881 - 3886
反应条件
1: SOCl2
2: 1.) n-BuLi / 1.) THF, hexane, -45 deg C, 1.5h, 2.) room temp.
3: NBS / benzoyl peroxide / CCl4 / 1 h / Heating; Irradiation
4: 96.4 percent / 6N HCl aq / Heating
View Scheme
参考文献
Meyers, A. I.; Avila, Walter B.
Journal of Organic Chemistry, 1981 , vol. 46, # 19 p. 3881 - 3886
反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -45 deg C, 1.5h, 2.) room temp.
2: NBS / benzoyl peroxide / CCl4 / 1 h / Heating; Irradiation
3: 96.4 percent / 6N HCl aq / Heating
View Scheme
参考文献
Meyers, A. I.; Avila, Walter B.
Journal of Organic Chemistry, 1981 , vol. 46, # 19 p. 3881 - 3886
反应条件
1: 98.1 percent / SOCl2
3: SOCl2
4: 1.) n-BuLi / 1.) THF, hexane, -45 deg C, 1.5h, 2.) room temp.
5: NBS / benzoyl peroxide / CCl4 / 1 h / Heating; Irradiation
6: 96.4 percent / 6N HCl aq / Heating
View Scheme
参考文献
Meyers, A. I.; Avila, Walter B.
Journal of Organic Chemistry, 1981 , vol. 46, # 19 p. 3881 - 3886
反应条件
1: acetic anhydride / Heating
2: L-Selectride / tetrahydrofuran / 2 h / Ambient temperature
View Scheme
参考文献
Makhlouf, Mansour A.; Rickborn, Bruce
Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4810 - 4811
反应条件
1: 1) s-BuLi, N,N,N,N-tetramethylethylene diamine / 1) THF, cyclohexane, -78 deg C, 1 h, 2) to room temperature, 12 h
2: NaBH4 / methanol / 3 h
3: aq. 2 N HCl / methanol / 1 h / Heating
View Scheme
参考文献
De Silva; Reed; Billedeau; Wang; Norris; Snieckus
Tetrahedron, 1992 , vol. 48, # 23 p. 4863 - 4878
参考文献
Gupta, Dahmendra N.; Hodge, Philip; Hurley, Peter N.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 391 - 394
