7-甲氧基苯并呋喃-2-甲酸合成路线 （共 16 条）
反应条件
borane-THF; boron trifluoride diethyl etherate in tetrahydrofuran
T=20°C; 18 h;
参考文献
Chen; Iakovleva; Kesten; Magano; Rodriguez; Sexton; Zhang; Lee
Organic Preparations and Procedures International, 2002 , vol. 34, # 6 p. 665 - 670
反应条件
1: aqueous hydrobromic acid; acetic acid
2: hydrogen chloride
View Scheme
参考文献
Reichstein et al.
Helvetica Chimica Acta, 1935 , vol. 18, p. 816,826
反应条件
hydrogen bromide; acetic acid
参考文献
SENOMYX, INC.; TACHDJIAN, Catherine; LI, Xiaodong; KARANEWSKY, Donald S.; FOTSING, Joseph; PATRON, Andrew; DARMOHUSODO, Vincent; SELCHAU, Victor; CHING, Brett
Patent: WO2011/159781 A2, 2011 ;
Location in patent: Page/Page column 70 ;
WO 2011/159781 A2
反应条件
sulfuric acid in dichloromethane
17 h; Reflux;
参考文献
Appleton, David R.; Pearce, A. Norrie; Copp, Brent R.
Tetrahedron, 2010 , vol. 66, # 27-28 p. 4977 - 4986
反应条件
thionyl chloride in methanol
参考文献
Nishiyama, Akira; Bougauchi, Masahiro; Kuroita, Takanobu; Minoguchi, Masanori; Morio, Yasunori; Kanzaki, Kouji
Patent: US2002/111358 A1, 2002 ;
反应条件
methanol in hexane; benzene
0.5 h;
参考文献
Merck and Co., Inc.
Patent: US6642237 B1, 2003 ;
Location in patent: Page/Page column 113 ;
