2,6-二氯吡嗪合成路线

NOVARTIS AG; BARSANTI, Paul, A.; HU, Cheng; JIN, Xianming; NG, Simon, C.; PFISTER, Keith, B.; SENDZIK, Martin; SUTTON, James
Patent: WO2012/101064 A1, 2012 ;
Location in patent: Page/Page column 84-85 ;
WO 2012/101064 A1

4774-14-52,6-二氯吡嗪+

442850-71-7

1010086-61-9

参考文献

Iwasawa, Yoshikuzu; Kato, Tetsuya; Kawanishi, Nobuhiko; Masutani, Kouta; Mita, Takashi; Nonoshita, Katsumasa; Ohkubo, Mitsuru
Patent: US2008/58347 A1, 2008 ;
Location in patent: Page/Page column 42 ;
US 20080058347 A1

4774-14-52,6-二氯吡嗪+

67-63-0异丙醇

1016698-79-5

参考文献

AMGEN INC.; WANG, Hui-Ling; CEE, Victor, C.; HERBERICH, Bradley, J.; JACKSON, Claire, L., M.; LANMAN, Brian, Alan; NIXEY, Thomas; PETTUS, Liping, H.; REED, Anthony, B.; WU, Bin; WURZ, Ryan; TASKER, Andrew
Patent: WO2012/129338 A1, 2012 ;
Location in patent: Page/Page column 196-197 ;
WO 2012/129338 A1

4774-14-52,6-二氯吡嗪+

676-58-4甲基氯化镁

108-50-92,6-二甲基吡嗪

参考文献

Dickschat, Jeroen S.; Reichenbach, Hans; Wagner-Doebler, Irene; Schulz, Stefan
European Journal of Organic Chemistry, 2005 , # 19 p. 4141 - 4153

4774-14-52,6-二氯吡嗪+

109-94-4甲酸乙酯

136866-27-8

参考文献

PFIZER INC.; NINKOVIC, Sacha; BRAGANZA, John Frederick; COLLINS, Michael Raymond; KATH, John Charles; LI, Hui; RICHTER, Daniel Tyler
Patent: WO2010/16005 A1, 2010 ;
Location in patent: Page/Page column 111-112 ;
WO 2010/016005 A1

参考文献

Neurogen Corporation
Patent: US2003/220348 A1, 2003 ;
US 20030220348 A1