2,2-二羟甲基丙酸合成路线

FRESENIUS KABI ONCOLOGY LTD; GUPTA, Nitin; HANDA, Vishal; PAL, Abir, Kumar; SINGH, Hemat, Kumar; LAHIRI, Saswata; DUBEY, Sushil, Kumar
Patent: WO2011/92564 A2, 2011 ;
Location in patent: Page/Page column 18-19 ;

4767-03-72,2-二羟甲基丙酸+

98-80-6苯硼酸

839720-60-45-甲基-2-苯基-1,3,2-二氧硼杂环-5-甲酸

参考文献

Chew, Warren; Shaw, Chia-Cheng
Patent: US2005/33046 A1, 2005 ;
Location in patent: Page/Page column 5; 7 ;

4767-03-72,2-二羟甲基丙酸+

77-76-92,2-二甲氧基丙烷

16837-14-22,2,5-三甲基-1,3-二恶烷-5-甲酸

参考文献

CADILA HEALTHCARE LIMITED
Patent: US2012/202988 A1, 2012 ;
Location in patent: Page/Page column 12 ;

4767-03-72,2-二羟甲基丙酸+

67-64-1丙酮

16837-14-22,2,5-三甲基-1,3-二恶烷-5-甲酸

参考文献

Welsh, Daniel J.; Jones, Simon P.; Smith, David K.
Angewandte Chemie, International Edition, 2009 , vol. 48, p. 4047 - 4051
Angewandte Chemie, 2009 , vol. 121, p. 4107 - 4111

4767-03-72,2-二羟甲基丙酸

162635-04-3西罗莫司脂化物

参考文献

CADILA HEALTHCARE LIMITED; DAVE, Mayank, Ghanshyambhai; PANDEY, Bipin
Patent: WO2011/51960 A2, 2011 ;

4767-03-72,2-二羟甲基丙酸

17872-59-2

参考文献

Ihre, Henrik; Hult, Anders; Soederlind, Erik
Journal of the American Chemical Society, 1996 , vol. 118, # 27 p. 6388 - 6395