N-甲基-1,2-苯二胺合成路线 （共 142 条）
反应条件
in dichloromethane 3 h; Heating;
参考文献
Li, Qun; Li, Tongmei; Woods, Keith W.; Gu, Wen-Zhen; Cohen, Jerry; Stoll, Vincent S.; Galicia, Tomas; Hutchins, Charles; Frost, David; Rosenberg, Saul H.; Sham, Hing L.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 11 p. 2918 - 2922
反应条件
N-methyl-pyrrolidine; selenium in tetrahydrofuran 1.) 31 kg/cm2, 100 degC, 20 h, 2.) 25 degC, 1 h;
参考文献
Yoshida, Tohru; Kambe, Nobuaki; Ogawa, Akiya; Sonoda, Noboru
Phosphorus and Sulfur and the Related Elements, 1988 , vol. 38, p. 137 - 148
反应条件
[DBU][HOAc] in neat (no solvent) T=120°C; P=67506.8 Torr; 24 h;
参考文献
Yu, Bo; Zhang, Hongye; Zhao, Yanfei; Chen, Sha; Xu, Jilei; Hao, Leiduan; Liu, Zhimin
ACS Catalysis, 2013 , vol. 3, # 9 p. 2076 - 2082
反应条件
1: aq.-ethanolic HCl View Scheme
参考文献
Duffin; Kendall
Journal of the Chemical Society, 1956 , p. 361,364
参考文献
Pinnow; Saemann
Chemische Berichte, 1899 , vol. 32, p. 2187
反应条件
1.1: hydrogenchloride / water / Reflux 1.2: pH 8 2.1: sodium periodate; sulfuric acid / water / 20 °C 2.2: 20 °C / pH 8 View Scheme
参考文献
WO2011/150156 A2, ;
WO 2011/150156 A2
参考文献
Liebigs Annalen der Chemie, , # 4 p. 542 - 556
反应条件
hydrogenchloride Heating;
参考文献
Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical, , vol. 25, # 12 p. 1092 - 1096
参考文献
Journal of the Chemical Society, , p. 1600,1602
反应条件
sulfur in dimethyl sulfoxide T=20 - 60°C; 2.58333 h;
参考文献
PFIZER INC.; NAIR, Sajiv Krishnan; PLANKEN, Simon Paul; PLEWE, Michael Bruno; VERNIER, William Francois; YANG, Yi; ZHU, Huichun
Patent: WO2011/27249 A2, 2011 ;
Location in patent: Page/Page column 58-59 ;
WO 2011/027249 A1
