19-羧基雄甾-4-烯-3,17-二酮合成路线 （共 4 条）
反应条件
pyridine 0.5 h; Heating;
参考文献
Ranjith, H.; Dharmaratne, W.; Kilgore, James L.; Roitman, Esther; Shackleton, Cedric; Caspi, Eliahu
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 13 p. 1529 - 1536
反应条件
1: 700 mg / pyridine / 1 h / 50 °C 2: 5.1 g / malonic acid / 19 h View Scheme
参考文献
Templeton, John F.; Ling, Yangzhi; Lin, Weiyang; Pitura, Randy J.; Marat, Kirk; Bridson, John N.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 9 p. 1149 - 1158
反应条件
1: 700 mg / pyridine / 1 h / 50 °C 2: 2.55 g / TsOH / benzene / 2 h / Heating 3: 1.) tBuOK, 2.) TsOH / 1.) Et2O, -30 deg C, 24 h, 2.) acetone, TsOH, 2 h View Scheme
参考文献
Templeton, John F.; Ling, Yangzhi; Lin, Weiyang; Pitura, Randy J.; Marat, Kirk; Bridson, John N.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 9 p. 1149 - 1158
反应条件
in diethyl ether Esterification;
参考文献
Templeton, John F.; Majgier-Baranowska, Helena; Marat, Kirk
Steroids, 2000 , vol. 65, # 4 p. 219 - 223
