2-CHLORO-2-PHENYLACETIC ACID合成路线 （共 66 条）
反应条件
Al(III) salt; tetrabutylammomium bromide in N,N-dimethyl-formamide P=18240 Torr; anode = Al 99.9percent ; cathode = Zn 99percent ; cathodic current density 100 A m-2;
参考文献
Silvestri, G.; Gambino, S.; Filardo, G.; Greco, G.; Gulotta, A.
Tetrahedron Letters, 1984 , vol. 25, # 38 p. 4307 - 4308
反应条件
potassium hydroxide in water T=0°C; 72 h;
参考文献
Reeve, Wilkins; McKee, James R.; Brown, Robert; Lakshmanan, Sitarama; McKee, Gertrude A.
Canadian Journal of Chemistry, 1980 , vol. 58, p. 485 - 493
反应条件
potassium hydroxide in water T=0°C; 72 h;
参考文献
Jozitsch
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1897 , vol. 29, p. 111
Chem. Zentralbl., 1897 , vol. 68, # I p. 1015
反应条件
tetra-n-butylammonium tetrafluoroborate in acetonitrile Electrolysis;
参考文献
Otero, M. Dolores; Batanero, Belen; Barba, Fructuoso
Tetrahedron Letters, 2006 , vol. 47, # 13 p. 2171 - 2173
反应条件
1: 40 g / potassium tert-butoxide / 2-methyl-propan-2-ol; benzene / 2 h / 0 °C 2: 10percent potassium hydroxide, 1percent potassium oleate / 1.5 h / -5 °C View Scheme
参考文献
Reeve, Wilkins; Tsuk, Ruth
Journal of Organic Chemistry, 1980 , vol. 45, # 25 p. 5214 - 5215
反应条件
1: HCl / diethyl ether 2: aq. CrO3, H2SO4 / acetone View Scheme
参考文献
Woolsey,N.F.; Khalil,M.H.
Journal of Organic Chemistry, 1975 , vol. 40, p. 3521 - 3528
反应条件
potassium hydroxide; potassium Oleate T=-5°C; 1.5 h; Yield given. Yields of byproduct given;
参考文献
Reeve, Wilkins; Tsuk, Ruth
Journal of Organic Chemistry, 1980 , vol. 45, # 25 p. 5214 - 5215
反应条件
potassium hydroxide in water T=0°C; 72 h; Product distribution;
参考文献
Reeve, Wilkins; McKee, James R.; Brown, Robert; Lakshmanan, Sitarama; McKee, Gertrude A.
Canadian Journal of Chemistry, 1980 , vol. 58, p. 485 - 493
反应条件
1: 63 percent / anhydrous aluminum chloride 2: 11.6 g / potassium hydroxyde / H2O / 72 h / 0 °C View Scheme
参考文献
Reeve, Wilkins; McKee, James R.; Brown, Robert; Lakshmanan, Sitarama; McKee, Gertrude A.
Canadian Journal of Chemistry, 1980 , vol. 58, p. 485 - 493
反应条件
1: thionyl chloride; N,N-dimethyl-formamide / tetrahydrofuran 2: water View Scheme
参考文献
Marzorati, Liliana; Fejfar, Jose L.; Tormena, Claudio F.; Vitta, Claudio Di
Tetrahedron Asymmetry, 2012 , vol. 23, # 10 p. 748 - 753
