2,2',3,3',4',6,6'-七-O-乙酰基-alpha-D-乳糖基溴化物合成路线 （共 37 条）
反应条件
1: 1.) HgO, HgBr2, CaSO4, 2.) HgBr2 / 1.) CHCl3, 20 h, 2.) toluene, nitromethane, 50 deg C, 24 h 2: BF3*Et2O / toluene / 3 h / 22 °C View Scheme
参考文献
Jansson, Karl; Ahlfors, Stefan; Frejd, Torbjoern; Kihlberg, Jan; Magnusson, Goeran; et al.
Journal of Organic Chemistry, 1988 , vol. 53, # 24 p. 5629 - 5647
反应条件
pyridine; sodium hydroxide 1) acetone, r.t., 2) 90 deg C, 50 min.; Yield given. Multistep reaction;
参考文献
Delay; Cizeau; Delmotte
Carbohydrate Research, 1992 , vol. 225, # 2 p. 179 - 188
反应条件
1: With iron(III) chloride in nitromethane T=25°C; 1 h; 2: With sodium methylate in methanol T=20°C; Zemplen deacetylation;
参考文献
Koto, Shinkiti; Hirooka, Motoko; Tashiro, Takako; Sakashita, Motokazu; Hatachi, Masaharu; Kono, Takayuki; Shimizu, Miho; Yoshida, Nahoko; Kurasawa, Sayaka; Sakuma, Natsuko; Sawazaki, Sunao; Takeuchi, Akihiro; Shoya, Naomi; Nakamura, Emi
Carbohydrate Research, 2004 , vol. 339, # 14 p. 2415 - 2424
反应条件
1: With Ag2CO3 in dichloromethane T=20°C; 5 h; 2: With methanol; sodium hydroxide in chloroform
参考文献
Zhao, Haisuo; Naito, Hiroyuki; Ueda, Yoshimi; Okada, Katsuhide; Sadagane, Kenji; Izumi, Minoru; Nakajima, Shuhei; Baba, Naomichi
Bioscience, Biotechnology and Biochemistry, 2008 , vol. 72, # 11 p. 3006 - 3010
反应条件
1: 1.) HgO, HgBr2, CaSO4, 2.) HgBr2 / 1.) CHCl3, 20 h, 2.) toluene, nitromethane, 50 deg C, 24 h 2: BF3*Et2O / toluene / 3 h / 22 °C View Scheme
参考文献
Jansson, Karl; Ahlfors, Stefan; Frejd, Torbjoern; Kihlberg, Jan; Magnusson, Goeran; et al.
Journal of Organic Chemistry, 1988 , vol. 53, # 24 p. 5629 - 5647
反应条件
mercury(II) cyanide Yield given;
参考文献
Journal of Carbohydrate Chemistry, , vol. 15, # 7 p. 831 - 855
反应条件
1: TBAHS; aq. Na2CO3 / CH2Cl2 / 3 h / 20 °C 2: NaOMe; MeOH View Scheme
参考文献
Wei, Jinhua; Lv, Xun; Lue, Yang; Yang, Gangzhu; Fu, Lifeng; Yang, Liu; Wang, Jianjun; Gao, Jianhui; Cheng, Shuihong; Duan, Qian; Jin, Cheng; Li, Xuebing
European Journal of Organic Chemistry, 2013 , # 12 p. 2414 - 2419
反应条件
1: With iron(III) chloride in nitromethane T=25°C; 1 h; 2: With sodium methylate in methanol T=20°C; Zemplen deacetylation;
参考文献
Carbohydrate Research, , vol. 339, # 14 p. 2415 - 2424
反应条件
1: With Ag2CO3 in dichloromethane T=20°C; 5 h; 2: With methanol; sodium hydroxide in chloroform
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 72, # 11 p. 3006 - 3010
反应条件
sodium azide; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate in dichloromethane 2 h; Ambient temperature;
参考文献
Aravind, Sivasubramanian; Park, William K. C.; Brochu, Stephane; Roy, Rene
Tetrahedron Letters, 1994 , vol. 35, # 42 p. 7739 - 7742
