2-羟基-2,2-双(2-噻吩)乙酸合成路线 （共 6 条）
反应条件
hydrogenchloride; acetic acid; tin(ll) chloride
参考文献
Blicke; Tsao
Journal of the American Chemical Society, 1944 , vol. 66, p. 1645,1646
反应条件
potassium hydroxide in ethanol
参考文献
Jeffries, Alfred T.; Moore, Kenneth C.; Ondeyka, Debra M.; Springsteen, Arthur W.; MacDowell, Denis W.H.
Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2885 - 2889
反应条件
1: 53 percent / 15 °C
2: 49 percent / KOH / ethanol
View Scheme
参考文献
Jeffries, Alfred T.; Moore, Kenneth C.; Ondeyka, Debra M.; Springsteen, Arthur W.; MacDowell, Denis W.H.
Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2885 - 2889
参考文献
Cardon; Lankelma
Journal of the American Chemical Society, 1948 , vol. 70, p. 4248
反应条件
1: With potassium hydroxide in ethanol; water
0.166667 h; Reflux;
2: With hydrogenchloride in ethanol; water
T=0°C; pH=1;
参考文献
Lange, Alexander; Krueger, Hartmut; Ecker, Bernhard; Tunc, Ali Veysel; Von Hauff, Elizabeth; Morana, Mauro
Journal of Polymer Science, Part A: Polymer Chemistry, 2012 , vol. 50, # 8 p. 1622 - 1635
反应条件
diethyl ether
Behandeln des Reaktionsprodukts mit wss. Salzsaeure;
参考文献
Blicke; Tsao
Journal of the American Chemical Society, 1944 , vol. 66, p. 1645,1646
