2-苯基-4-五亚乙基六胺-2-醇合成路线 （共 59 条）
反应条件
1: 3 percent / MeI, Ce powder, I2 / tetrahydrofuran / 3 h / -20 °C 2: 1) Ce powder, I2, 2) PhI / 1) THF, -20 deg C, 2) THF, -20 deg C, 3 h, var. reag. in 2) : Me-, Et- and allyl iodide View Scheme
参考文献
Fukuzawa, Shin-ichi; Fujinami, Tatsuo; Sakai, Shizuyoshi
Journal of Organometallic Chemistry, 1986 , vol. 299, p. 179 - 186
反应条件
(i) <nBu4N>F, THF, (ii) HCl, MeOH; Multistep reaction;
参考文献
Pilcher, Anthony S.; DeShong, Philip
Journal of Organic Chemistry, 1996 , vol. 61, # 20 p. 6901 - 6905
反应条件
magnesium; tetrakis(triphenylphosphine) palladium(0) 1.) 0 deg C, 10 min; 2.) room temperature, overnight;; Yield given. Multistep reaction;
参考文献
Araki, Shuki; Ohmura, Masayuki; Butsugan, Yasuo
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 5 p. 1607 - 1608
反应条件
1.1: [Pt(PPh3)4] / toluene / 6 h / 80 °C / |Inert atmosphere; |Schlenk technique 2.1: methyllithium / tetrahydrofuran; ethylene glycol dimethyl ether / 0.17 h / -78 °C / |Inert atmosphere; |Schlenk technique 2.2: 1 h / -78 - 0 °C / |Inert atmosphere; |Schlenk technique 2.3: 2 h / 23 °C / |Inert atmosphere; |Schlenk technique View Scheme
参考文献
Wommack, Andrew J.; Kingsbury, Jason S.
Tetrahedron Letters, 2014 , vol. 55, # 20 p. 3149 - 3152
反应条件
Pr 1.) THF, 20 deg C, 2.) -20 deg C;
参考文献
Gailyunas, G. A.; Biktimirov, R. Kh.; Monakov, Yu. B.; Tolstikov, G. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1985 , vol. 34, p. 2629
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1985 , # 12 p. 2830 - 2831
反应条件
1: (1,2-epoxy-1-methylethyl)-benzene; methylidene triphenyl phosphorane in benzene Heating; 2: formaldehyd in benzene Heating;
参考文献
Okuma, Kentaro; Hirose, Yoshitaka; Shioji, Kosei
Chemistry Letters, 2002 , # 4 p. 438 - 439
反应条件
indium 1.) DMA, 0 deg C, 1 h, 2.) 1 h; Yield given. Multistep reaction;
参考文献
Hirashita, Tsunehisa; Kamei, Toshiya; Horie, Tomoaki; Yamamura, Hatsuo; Kawai, Masao; Araki, Shuki
Journal of Organic Chemistry, 1999 , vol. 64, # 1 p. 172 - 177
反应条件
bis-(2-hydroxy-ethyl)-amine 1.) from 80 deg C to 100 deg C, 3 h, 2) from 120 deg C to 160 deg C, 2 h; Multistep reaction;
参考文献
Zhou, Weike; Liang, Shaofang; Yu, Su; Luo, Weiming
Journal of Organometallic Chemistry, 1993 , vol. 452, # 1.2 p. 13 - 18
参考文献
Kociolek, Martin G.; Hongfa, Chayanant
Tetrahedron Letters, 2003 , vol. 44, # 9 p. 1811 - 1813
反应条件
(i) pentane, (ii) H2NCH2CH2OH; Multistep reaction;
参考文献
Kramer,G.W.; Brown,H.C.
Journal of Organic Chemistry, 1977 , vol. 42, p. 2292 - 2299
