1: With copper(II) sulfate; acetic acid; sodium chloride T=50°C; 0.5 h; 2: With acetic acid T=85°C; 6 h;

1: 81 percent / Et3N / CH2Cl2 / 1.5 h / 0 °C 2: 91 percent / m-CPBA / CH2Cl2 / 1 h / 0 °C 3: 25 percent / CH3SO3H / CCl4 / 0.33 h / Heating 4: 90 percent / Raney Ni / ethanol / 2 h / Heating 5: POCl3; K2CO3 / acetonitrile / 0.67 h / 60 °C 6: NaBH4 / methanol / 1 h / Heating View Scheme