反应条件
1: 1.) LDA, 2.) SOCl2 / 1.) THF, hexane, -70 deg C, 3 h, 2.) pyridine, -20 deg C, 1 h 2: 91.4 percent / i-Bu2AlH / toluene / 0.5 h / -20 °C 3: 1.) Li, NH3, 2.) (CO2H)2*H2O / 1) EtOH, Et2O-THF, -75 deg C, 0.5 h, 2) aq.MeOH, 50 deg C, 2 h; room temp., overnight View Scheme
参考文献
Terasawa; Okada
Tetrahedron, 1986 , vol. 42, # 2 p. 537 - 545
