3,4-二氢-2,2-二甲基-2H-萘并[1,2-B]吡喃-5,6-二酮合成路线 （共 56 条）
反应条件
1: 100 percent / H2 / 10 percent Pd/C / ethyl acetate / 1 h / 2068.59 Torr 2: 62 percent / cerrium ammonium nitrate; H2O / acetonitrile / 0.5 h / 0 - 5 °C View Scheme
参考文献
Wang, Xue; Chen, Ye; Lee, Yong Rok
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 1 p. 153 - 156
反应条件
air; sulfuric acid; acetic acid
参考文献
Hooker
Journal of the American Chemical Society, 1936 , vol. 58, p. 1190,1195
反应条件
1: platinum; ethanol / Hydrogenation 2: acetic acid; concentrated sulfuric acid; air View Scheme
参考文献
Hooker
Journal of the American Chemical Society, 1936 , vol. 58, p. 1190,1195
反应条件
1: With 2,3-dicyano-5,6-dichloro-p-benzoquinone in benzene 8 h; Reflux; 2: With sulfuric acid 1 h; Inert atmosphere;
参考文献
Eyong, Kenneth O.; Kumar, Ponminor S.; Kuete, Victor; Folefoc, Gabriel N.; Nkengfack, Ephriam A.; Baskaran, Sundarababu
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 20 p. 5387 - 5390
反应条件
sodium nitrite in water; acetic acid T=80°C; 6 h; Further byproducts given;
参考文献
Singh; Jain; Krishna
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 2 p. 89 - 92
反应条件
sodium nitrite in water; acetic acid T=80°C; 6 h; Further byproducts given;
参考文献
Singh; Jain; Krishna
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 2 p. 89 - 92
反应条件
1: 40 percent / lithium hydride / dimethylsulfoxide / 45 deg C, 5 h; 25 deg C, 10 h 2: H2SO4 / H2O / 25 °C View Scheme
参考文献
Schaffner-Sabba, Karl; Schmidt-Ruppin, Karl H.; Wehrli, Walter; Schuerch, ALfred R.; Wasley, Jan W. F.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 990 - 994
反应条件
1: 40 percent / lithium hydride / dimethylsulfoxide / 45 deg C, 5 h; 25 deg C, 10 h 2: H2SO4 / H2O / 25 °C View Scheme
参考文献
Schaffner-Sabba, Karl; Schmidt-Ruppin, Karl H.; Wehrli, Walter; Schuerch, ALfred R.; Wasley, Jan W. F.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 990 - 994
反应条件
acetic acid; sodium nitrite in water T=80°C; 6 h;
参考文献
Singh, Pahup; Krishna, Vivek; Khandelwal, Poonam; Sharma, Kuldeep K.; Sharma
Journal of the Indian Chemical Society, 2010 , vol. 87, # 1 p. 85 - 95
反应条件
in water pH=6.8 - 7; Aqueous phosphate buffer; Product distribution / selectivity;
参考文献
ARQULE, INC.
Patent: WO2008/134088 A1, 2008 ;
Location in patent: Page/Page column 21-22 ;
