dihydrogen peroxide in tetrahydrofuran 1 h; Ambient temperature;

dihydrogen peroxide in dichloromethane 0.5 h; Ambient temperature;

1: 89 percent / m-chloroperbenzoic acid / CH2Cl2 / -15 - -5 °C 2: 1.) trifluoroacetic anhydride, 2.) triethylamine / 1.) CH2Cl2, RT, 3 h, 2.) CH2Cl2, RT, 2 h 3: 70 mg / oxone / tetrahydrofuran; H2O / 72 h / Ambient temperature 4: 19 percent / NaBH4 / tetrahydrofuran; D2O / 0.25 h / Ambient temperature; other vinyl sulfoxides, other reagents, other solvents, var. time View Scheme

1: 70 mg / oxone / tetrahydrofuran; H2O / 72 h / Ambient temperature 2: 19 percent / NaBH4 / tetrahydrofuran; D2O / 0.25 h / Ambient temperature; other vinyl sulfoxides, other reagents, other solvents, var. time View Scheme

1: 31 percent / NaBD4 / tetrahydrofuran; H2O / 2.5 h / Ambient temperature 2: 70 mg / oxone / tetrahydrofuran; H2O / 72 h / Ambient temperature 3: 19 percent / NaBH4 / tetrahydrofuran; D2O / 0.25 h / Ambient temperature; other vinyl sulfoxides, other reagents, other solvents, var. time View Scheme

1: 13 percent / NaBH4 / ethanol / 0.75 h / 0 °C 2: 95 percent / pyridine / 24 h / 0 °C 3: 76 percent / Li2CO3 / dimethylformamide / 3 h / 140 °C 4: 60 percent / xylene; propan-2-ol / 4 h / Ambient temperature; Irradiation 5: 1) LDA, 2) HMPA / 1) THF, hexane, -78 deg C, 1 h, 2) THF, a) -78 deg C, 1 h, b) -35 deg C, 45 min 6: 1M aq.NaOH / aq. ethanol / 0.75 h / Heating 7: Et3N / tetrahydrofuran / 3 h / 0 °C 8: 0.25 M aq.NaOH / 30 h / 50 °C 9: 80 percent / 30percent H2O2 / tetrahydrofuran / 1 h / Ambient temperature View Scheme

1: 1.) lithium isopropylcyclohexylamine / 1.) hexane, THF, -78 deg C, 1 h, 2.) hexane, THF, from -78 deg C to -20 deg C 2: 30 mg / aq. H2O2 / CH2Cl2 / 0.5 h / Ambient temperature View Scheme

1: 92 percent / LiBr, Li2CO3 / dimethylformamide / 2.25 h / 140 °C 2: 60 percent / xylene; propan-2-ol / 4 h / Ambient temperature; Irradiation 3: 1) LDA, 2) HMPA / 1) THF, hexane, -78 deg C, 1 h, 2) THF, a) -78 deg C, 1 h, b) -35 deg C, 45 min 4: 1M aq.NaOH / aq. ethanol / 0.75 h / Heating 5: Et3N / tetrahydrofuran / 3 h / 0 °C 6: 0.25 M aq.NaOH / 30 h / 50 °C 7: 80 percent / 30percent H2O2 / tetrahydrofuran / 1 h / Ambient temperature View Scheme

1: 60 percent / xylene; propan-2-ol / 4 h / Ambient temperature; Irradiation 2: 1) LDA, 2) HMPA / 1) THF, hexane, -78 deg C, 1 h, 2) THF, a) -78 deg C, 1 h, b) -35 deg C, 45 min 3: 1M aq.NaOH / aq. ethanol / 0.75 h / Heating 4: Et3N / tetrahydrofuran / 3 h / 0 °C 5: 0.25 M aq.NaOH / 30 h / 50 °C 6: 80 percent / 30percent H2O2 / tetrahydrofuran / 1 h / Ambient temperature View Scheme

1: 76 percent / Li2CO3 / dimethylformamide / 3 h / 140 °C 2: 60 percent / xylene; propan-2-ol / 4 h / Ambient temperature; Irradiation 3: 1) LDA, 2) HMPA / 1) THF, hexane, -78 deg C, 1 h, 2) THF, a) -78 deg C, 1 h, b) -35 deg C, 45 min 4: 1M aq.NaOH / aq. ethanol / 0.75 h / Heating 5: Et3N / tetrahydrofuran / 3 h / 0 °C 6: 0.25 M aq.NaOH / 30 h / 50 °C 7: 80 percent / 30percent H2O2 / tetrahydrofuran / 1 h / Ambient temperature View Scheme