5,5-二甲基-2-环己烯-1-酮合成路线 （共 67 条）
反应条件
magnesium; copper(l) chloride in diethyl ether
1.) -20 deg C; 2.) -40 deg C, then rt.;
参考文献
Kato; Hattori; Kawai; Sawa
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3915 - 3923
反应条件
magnesium; copper(l) chloride in diethyl ether
1.) -20 deg C; 2.) -40 deg C, then rt.;
参考文献
Kato; Hattori; Kawai; Sawa
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3915 - 3923
反应条件
1: 30 percent / 1.) Mg; 2.) CuCl / diethyl ether / 1.) -20 deg C; 2.) -40 deg C, then rt.
2: 70 percent / 47percent aq. HBr / 2 h / 120 - 130 °C
View Scheme
参考文献
Kato; Hattori; Kawai; Sawa
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3915 - 3923
反应条件
magnesium; copper(l) chloride in diethyl ether
1.) -20 deg C; 2.) -40 deg C, then rt.;
参考文献
Kato; Hattori; Kawai; Sawa
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3915 - 3923
反应条件
magnesium; copper(l) chloride in diethyl ether
1.) -20 deg C; 2.) -40 deg C, then rt.;
参考文献
Kato; Hattori; Kawai; Sawa
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 3915 - 3923
反应条件
1: 91 percent / LiAlH4
2: 81 percent / propionic acid / 36 h / 138 °C
3: 95 percent / H2 / 10percent Pd/C / ethanol
4: LiAlH4
5: 76 percent / pyridinium chlorochromate, NaOAc / CH2Cl2 / 2 h
View Scheme
参考文献
Wawrzenczyk, Czeslaw; Lochynski, Stanislaw
Monatshefte fuer Chemie, 1985 , vol. 116, p. 99 - 110
反应条件
in diethyl ether; acetic acid
参考文献
Imperial Chemical Industries Limited
Patent: US4102896 A1, 1978 ;
