5,5-二甲基-2-环己烯-1-酮合成路线 （共 67 条）
反应条件
triethylsilane; palladium diacetate; 1,3-bis-(diphenylphosphino)propane; triethylamine in N,N-dimethyl-formamide
0.666667 h; Ambient temperature;
参考文献
Kotsuki; Datta; Hayakawa; Suenaga
Synthesis, 1995 , # 11 p. 1348 - 1350
反应条件
toluene-4-sulfonic acid in tetrahydrofuran
retro-Michael reaction; 48 h; Heating;
参考文献
Binot, Gregori; Quiclet-Sire, Beatrice; Saleh, Twana; Zard, Samir Z.
Synlett, 2003 , # 3 p. 382 - 386
参考文献
Ligand Pharmaceuticals Incorporated
Patent: US5677336 A1, 1997 ;
反应条件
in tetrahydrofuran
T=-78°C;
参考文献
Posner,G.H. et al.
Journal of the American Chemical Society, 1973 , vol. 95, # 23 p. 7788 - 7800
反应条件
hydrogenchloride in ethanol
electrolysis; Yield given;
参考文献
Matschiner, H.; Voigtlaender, R.; Schick, H.; Lund, H.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1980 , vol. 34, # 2 p. 136 - 138
参考文献
Bartel, S.; Bohlmann, F.
Tetrahedron Letters, 1989 , vol. 30, # 6 p. 685 - 688
反应条件
1,1-dimethylpropan-1-ol; nickel diacetate; sodium hydride in ethylene glycol dimethyl ether
1 h; Ambient temperature;
参考文献
Martinez, A. Garcia; Alvarez, R. Martinez; Casado, M. Madueno; Subramanian, L. R.; Hanack, M.
Tetrahedron, 1987 , vol. 43, # 1 p. 275 - 280
反应条件
diisobutylaluminium hydride; toluene-4-sulfonic acid
1.) irradiation, hexane, 24 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Baldwin, S. W.; Wilkinson, J. M.
Journal of the American Chemical Society, 1980 , vol. 102, # 10 p. 3634 - 3635
反应条件
1: trichlorophosphate / chloroform / 20 °C / Reflux
2: potassium iodide; zinc / methanol
View Scheme
参考文献
F. HOFFMANN-LA ROCHE AG; CHEN, Li; LIN, Xianfeng; QIU, Zongxing; TANG, Guozhi; WANG, Lisha; WU, Jim Zhen; YANG, Wengang
Patent: WO2011/95576 A1, 2011 ;
反应条件
sulfuric acid in acetone
2 h; Heating; Yield given;
参考文献
Matoba, Katsuhide; Tokizawa, Minoru; Morita, Takashi; Yamazaki, Takao
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 1 p. 368 - 372
