2-(苯磺酰甲基)苯甲醛合成路线 （共 13 条）
反应条件
1.1: TMSOTf 2.1: BuLi / tetrahydrofuran; hexane / 1 h / -78 °C 2.2: tetrahydrofuran; hexane / 1 h / -78 °C 3.1: tetrahydrofuran; hexane / 2 h 4.1: t-BuOK / tetrahydrofuran; hexane / 3.67 h / 0 - 20 °C 5.1: 98 percent / p-TsOH; H2O / acetone / 16 h / 40 °C 6.1: NaBH4 View Scheme
参考文献
Orita, Akihiro; Yoshioka, Naonori; Struwe, Petra; Braier, Arnold; Beckmann, Anke; Otera, Junzo
Chemistry--A European Journal, 1999 , vol. 5, # 4 p. 1355 - 1363
反应条件
1: potassium tert-butoxide / 2-methyl-propan-2-ol; tetrahydrofuran / 6 h / 20 °C
2: 155 mg / aq. HCl / tetrahydrofuran; 2-methyl-propan-2-ol; methanol / 1 h / 20 °C
View Scheme
参考文献
Patra, Asit; Ghorai, Sujit K.; De, Saroj R.; Mal, Dipakranjan
Synthesis, 2006 , # 15 p. 2556 - 2562
反应条件
1: With diethyl chlorophosphate; lithium hexamethyldisilazane in tetrahydrofuran
T=-78 - 20°C; 2 h;
2: With lithium diisopropyl amide in tetrahydrofuran; hexane
T=-78°C; 2 h; Further stages.;
参考文献
Orita, Akihiro; Hasegawa, Daiki; Nakano, Takehiko; Otera, Junzo
Chemistry - A European Journal, 2002 , vol. 8, # 9 p. 2000 - 2004
