2,7-二-(1-叔-丁氧羰基吡咯-2-基)乙炔基-1,8-萘啶合成路线 （共 3 条）
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran
T=20°C; Sonogashira coupling; 40 h;
参考文献
Liao, Jen-Hai; Chen, Chao-Tsen; Chou, He-Chun; Cheng, Chung-Chih; Chou, Pi-Tai; Fang, Jim-Min; Slanina, Zdenek; Chow, Tashin J.
Organic Letters, 2002 , vol. 4, # 18 p. 3107 - 3110
反应条件
1: 79 percent / triethylamine; CuI / Pd(PPh3)2Cl2 / dioxane / 0.33 h / 80 °C
2: 84 percent / KF; MeOH / 6 h / 20 °C
3: 78 percent / triethylamine; CuI / Pd(PPh3)2Cl2 / tetrahydrofuran / 40 h / 20 °C
View Scheme
参考文献
Fang, Jim-Min; Selvi, Srinivasan; Liao, Jen-Hai; Slanina, Zdenek; Chen, Chao-Tsen; Chou, Pi-Tai
Journal of the American Chemical Society, 2004 , vol. 126, # 11 p. 3559 - 3566
反应条件
1: 84 percent / KF; MeOH / 6 h / 20 °C
2: 78 percent / triethylamine; CuI / Pd(PPh3)2Cl2 / tetrahydrofuran / 40 h / 20 °C
View Scheme
参考文献
Fang, Jim-Min; Selvi, Srinivasan; Liao, Jen-Hai; Slanina, Zdenek; Chen, Chao-Tsen; Chou, Pi-Tai
Journal of the American Chemical Society, 2004 , vol. 126, # 11 p. 3559 - 3566
