(3,5-二甲氧基苯基)乙酸合成路线 （共 46 条）
反应条件
1.1: LiAlH4 / tetrahydrofuran / 3 h / 20 °C 1.2: 97 percent / Na/K tartrate / tetrahydrofuran / 1 h / 20 °C 2.1: 86 percent / PBr3 / CH2Cl2 / 1 h / 20 °C 3.1: 83 percent / dimethylformamide / 1 h 4.1: 90 percent / conc. HCl / 2.5 h / Heating View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 4-5 p. 583 - 594
反应条件
potassium permanganate; sodium periodate; potassium carbonate in water; tert-butyl alcohol T=20°C; Lemieux-van Rudloff oxidation; 4 h;
参考文献
Chinese Journal of Chemistry, , vol. 28, # 6 p. 1041 - 1043
反应条件
1: potassium phosphate; tris-(o-tolyl)phosphine / tris-(dibenzylideneacetone)dipalladium(0) / tetrahydrofuran / 16 h / 20 °C / Sealed; Inert atmosphere 2: trifluoroacetic acid; triethylsilane / dichloromethane / 3 h / 0 °C View Scheme
参考文献
WO2011/123937 A1, ;
WO 2011/123937 A1
反应条件
potassium hydroxide in ethanol
参考文献
Tetrahedron, , vol. 37, # 23 p. 4059 - 4067
反应条件
1: (i) LiAlH4, (ii) PBr3 2: ethanol 3: NaOH / methanol View Scheme
参考文献
Tetrahedron, , vol. 18, p. 1519 - 1526
反应条件
sodium hydroxide Erhitzen des Reaktionsprodukts mit wss. Natronlauge;
参考文献
J. Fac. Sci. HokkaidoChem.Abstr., , vol. <III> 3, p. 1,12
J. Fac. Sci. HokkaidoChem.Abstr., , p. 7887
反应条件
1,4-dioxane; silver nitrate; sodium thiosulfate
参考文献
Itsuu Kenkyusho Nempo, , # 4 p. 1,3; engl. Ref. S. 45, 48
Chem.Abstr., , p. 1075
Journal of the Chemical Society, , p. 1104,1108
反应条件
1: 1) SOCl2 3: base hydrolysis View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 23 p. 2663 - 2666
反应条件
1: diethyl ether 2: Ag2O 3: aqueous NaOH View Scheme
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 9, p. 246,249
反应条件
water; silver(l) oxide 1) Et2O; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 35, # 9 p. 1367 - 1370
