N-Cbz-L-天冬氨酸 1-甲酯合成路线

67-56-1甲醇+4515-23-5Z-天冬氨酸酸酐→4668-42-2N-Cbz-L-天冬氨酸 1-甲酯

参考文献

DAEWOONG PHARMACEUTICAL CO., LTD.; CHOI, Soo Jin; LEE, Byung Goo; OH, Seong Soo; KIM, Yong Tae; EO, Jin Yong; KIM, Hung Sop
Patent: WO2012/148246 A2, 2012 ;
Location in patent: Page/Page column 13 ;

4668-37-5N-苄氧羰基天冬氨酰胺甲基酯→4668-42-2N-Cbz-L-天冬氨酸 1-甲酯

参考文献

Adams, David R.; Bailey, Patrick D.; Collier, Ian D.; Heffernan, John D.; Stokes, Stephen
Chemical Communications, 1996 , # 3 p. 349 - 350

67-56-1甲醇+1152-61-0N-CBZ-L-天冬氨酸→4668-42-2N-Cbz-L-天冬氨酸 1-甲酯

参考文献

Nuijens, Timo; Kruijtzer, John A.W.; Cusan, Claudia; Rijkers, Dirk T.S.; Liskamp, Rob M.J.; Quaedflieg, Peter J.L.M.
Tetrahedron Letters, 2009 , vol. 50, # 23 p. 2719 - 2721

67-56-1甲醇+57933-83-2异丙烯基氯甲酸酯+1152-61-0N-CBZ-L-天冬氨酸→3160-47-2N-苄氧羰基-L-天冬氨酸4-甲酯+4668-42-2N-Cbz-L-天冬氨酸 1-甲酯

参考文献

Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668

1152-61-0N-CBZ-L-天冬氨酸+79-22-1氯甲酸甲酯→3160-47-2N-苄氧羰基-L-天冬氨酸4-甲酯+4668-42-2N-Cbz-L-天冬氨酸 1-甲酯

参考文献

Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668

124-41-4甲醇钠+23632-66-8(S)-(+)-3(苄氧羰基)-5-氧代-4-恶唑啉乙酸→35909-93-4+1428260-93-8+4668-42-2N-Cbz-L-天冬氨酸 1-甲酯

参考文献

Chandan, Nandkishkor; Moloney, Mark G.
Tetrahedron Letters, 2013 , vol. 54, # 15 p. 1987 - 1990

63327-57-1N-[苄氧羰基]-L-天冬氨酸 4-叔丁酯 1-甲酯→4668-42-2N-Cbz-L-天冬氨酸 1-甲酯

参考文献

Misiti; Santaniello; Zappia
Synthetic Communications, 1992 , vol. 22, # 6 p. 883 - 891

15545-10-5N-[(苄氧基)羰基]-L-组氨酸甲酯→4668-42-2N-Cbz-L-天冬氨酸 1-甲酯+137816-71-8

参考文献

Ranganathan, Subramania; Ranganathan, Darshan; Bhattacharyya, Dipti
Tetrahedron Letters, 1991 , vol. 32, # 40 p. 5615 - 5618

67-56-1甲醇+1152-61-0N-CBZ-L-天冬氨酸+79-22-1氯甲酸甲酯→3160-47-2N-苄氧羰基-L-天冬氨酸4-甲酯+4668-42-2N-Cbz-L-天冬氨酸 1-甲酯

参考文献

Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668

35909-92-3N-(苄氧羰基)-L-苯丙氨酸甲酯→4668-42-2N-Cbz-L-天冬氨酸 1-甲酯

参考文献

Ranganathan; Muraleedharan; Bhattacharyya; Kundu
Journal of the Indian Chemical Society, 1998 , vol. 75, # 10-12 p. 583 - 589