N,N-二甲基甲酰胺二甲基缩醛合成路线 （共 679 条）
反应条件
in N,N-dimethyl-formamide; acetonitrile
参考文献
Bayer Aktiengesellschaft
Patent: US5466800 A1, 1995 ;
反应条件
2,4,6-tri-(tert-butyl)phenol T=100 - 115°C; 90 h; continuous removal of methanol by distillation;
参考文献
Mohacsi, Erno
Synthetic Communications, 1985 , vol. 15, # 8 p. 723 - 726
反应条件
hydrazine hydrate 1.) reflux, 16 h; 2.) MeOH, reflux, 1 h; Yield given. Multistep reaction;
参考文献
Halcrow, Malcolm A.; McInnes, Eric J. L.; Mabbs, Frank E.; Scowen, Ian J.; McPartlin, Mary; Powell, Harold R.; Davies, John E.
Journal of the Chemical Society - Dalton Transactions, 1997 , # 21 p. 4025 - 4035
反应条件
T=75°C; 0.0833333 h;
参考文献
Monatshefte fuer Chemie, , vol. 113, p. 731 - 744
Heterocycles, , vol. 19, # 2 p. 339 - 342
反应条件
in chloroform 2 h; Heating; Product distribution;
参考文献
Monatshefte fuer Chemie, , vol. 118, p. 399 - 408
反应条件
in toluene 3 h; Heating;
参考文献
Monatshefte fuer Chemie, , vol. 113, p. 731 - 744
Heterocycles, , vol. 19, # 2 p. 339 - 342
反应条件
1: in tetrahydrofuran Industry scale; 2: With acetic acid; hydrazine in tetrahydrofuran T=25 - 67°C; Industry scale; Product distribution / selectivity;
参考文献
US2006/258706 A1, ;
Page/Page column 18; 20 ;
反应条件
sodium methylate 1.) acetonitrile, reflux, 12 h, 2.) DMF, 100 deg C, 5 h; Yield given. Multistep reaction;
参考文献
Zeneca Limited
Patent: US5521179 A1, 1996 ;
参考文献
Ionkin, A. S.; Arbuzov, B. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 7.2 p. 1489 - 1491
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 7 p. 1639 - 1641
反应条件
1: With pyrrolidine in 1,4-dioxane T=102°C; Leimgruber-Batcho Indole Synthesis; 5 h; RefluxInert atmosphere; 2: With hydrazine hydrate in 1,4-dioxane T=45°C; Leimgruber-Batcho Indole Synthesis; 1 h;
参考文献
Chen, Jinchun; Zhang, Zhikai; Liu, Sujing; Yang, Cuiyun; Xia, Chuanhai
RSC Advances, 2014 , vol. 4, # 9 p. 4672 - 4675
