2-苯基吡啶-4-羧酸甲酯合成路线 （共 12 条）
反应条件
1.1: 62 percent / NaH; Pd(PPh3)4 / tetrahydrofuran / 20 °C
2.1: O3 / CH2Cl2; methanol / 0 °C
2.2: 77 percent / PPh3 / CH2Cl2; methanol / 19 h / 0 - 20 °C
3.1: 82 percent / NH3 / ethanol; CH2Cl2 / 16 h / 20 °C
View Scheme
参考文献
Craig, Donald; Henry, Gavin D.
Tetrahedron Letters, 2005 , vol. 46, # 15 p. 2559 - 2562
反应条件
T=80°C; k= 2.6E-4 mol1-sec-1; add of phenyl N-tert-butylnitrone as inhibitor; var.: in benzene; Product distributionRate constantMechanism;
参考文献
Court, J.; Vidal, S.; Bonnier, J. M.
Tetrahedron, 1988 , vol. 44, # 21 p. 6623 - 6632
