4-甲基-2-苯基-1,3-噁唑-5-羧酸乙酯合成路线 （共 9 条）
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride in tetrahydrofuran T=0°C; 1 h;
参考文献
Yamane, Taihei; Mitsudera, Hiroyuki; Shundoh, Takatsugu
Synthesis, 2004 , # 17 p. 2825 - 2832
反应条件
1: ethyl acetoacetate With PhI(ODNs)OH
0.0111111 h; microwave irradiation;
2: benzamide 0.0333333 h; microwave irradiation;
参考文献
Lee, Jong Chan; Choi, Hyun Jung; Lee, Yong Chan
Tetrahedron Letters, 2003 , vol. 44, # 1 p. 123 - 125
参考文献
Prager, Rolf H.; Smith, Jason A.; Weber, Ben; Williams, Craig M.
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 17 p. 2665 - 2672
反应条件
1: K2CO3 / dimethylformamide / 2 h / 50 °C
2: CH3COONH4; CH3COOH / 24 h / Heating
View Scheme
参考文献
Yamane, Taihei; Mitsudera, Hiroyuki; Shundoh, Takatsugu
Synthesis, 2004 , # 17 p. 2825 - 2832
反应条件
1: K2CO3 / dimethylformamide / 2 h / 50 °C
2: CH3COONH4; CH3COOH / 24 h / Heating
View Scheme
参考文献
Yamane, Taihei; Mitsudera, Hiroyuki; Shundoh, Takatsugu
Synthesis, 2004 , # 17 p. 2825 - 2832
反应条件
in acetic acid
3 h; Heating;
参考文献
Cornwall, Philip; Dell, Colin P.; Knight, David W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 10 p. 2417 - 2428
反应条件
potassium hydroxide in ethanol; water
48 h; Ambient temperature;
参考文献
Cornwall, Philip; Dell, Colin P.; Knight, David W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 10 p. 2417 - 2428
参考文献
Gruppo Lepetit S.p.A.
Patent: US4072689 A1, 1978 ;
参考文献
Tarzia,G. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 263 - 270
