3-(4-甲基苯甲酰)丙酸合成路线 （共 57 条）
反应条件
1: sodium acetate; hydrazine hydrate / methanol / 6 h / Reflux 2: trichlorophosphate / 6 h / Heating 3: hydrazine hydrate / ethanol / 16 h / Reflux View Scheme
参考文献
Islam, Mojahidul; Siddiqui, Anees A.
Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 5 p. 555 - 562
反应条件
1: 58 percent / Zn-Hg, cc. HCl / 15 h / Heating 2: 67 percent / p-toulenesulphonic acid / benzene / 18 h / Heating 3: 100 percent / diethyl ether / 24 h / Ambient temperature 4: polyphosphoric acid / 9 h / 50 - 55 °C View Scheme
参考文献
Mathur, Naresh C.; Snow, Miles S.; Young, Kent M.; Pincock, James A.
Tetrahedron, 1985 , vol. 41, # 8 p. 1509 - 1516
反应条件
1: sodium acetate; hydrazine hydrate / methanol / 6 h / Reflux 2: trichlorophosphate / 6 h / Heating View Scheme
参考文献
Islam, Mojahidul; Siddiqui, Anees A.
Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 5 p. 555 - 562
反应条件
sodium hydroxide; sodium hydrogencarbonate; sodium carbonate; potassium hexacyanoferrate(III); osmium(VIII) oxide in water T=36.85°C; pH=10.33; Kinetics; Further Variations:pH-values;
参考文献
Reddy, Cherkupally Sanjeeva; Manjari, Padma Sunitha
Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, 2010 , vol. 49, # 4 p. 418 - 424
反应条件
1: 58 percent / Zn-Hg, cc. HCl / 15 h / Heating 2: 67 percent / p-toulenesulphonic acid / benzene / 18 h / Heating View Scheme
参考文献
Mathur, Naresh C.; Snow, Miles S.; Young, Kent M.; Pincock, James A.
Tetrahedron, 1985 , vol. 41, # 8 p. 1509 - 1516
反应条件
in acetic acid Heating;
参考文献
Volynets, N. F.; Smartseva, I. V.; Khramova, I. V.; Pavlova, L. A.
Journal of Organic Chemistry USSR (English Translation), 1984 , p. 1604 - 1608
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 8 p. 1760 - 1764
反应条件
1: 75 percent / K2CO3 / acetone / Heating 2: 50 percent / CH3COONa / methanol / Heating View Scheme
参考文献
Khan; Siddiqui
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 8 p. 614 - 619
反应条件
1: Zn, aq. HCl 2: aq. H2SO4 3: (i), (ii) (heating) 4: H2 / Pd-C View Scheme
参考文献
Jefferies, Latisha R.; Cook, Silas P.
Organic Letters, 2014 , vol. 16, # 7 p. 2026 - 2029
反应条件
1: H2SO4 / Heating 2: 100 percent / bromine / AlCl3 / diethyl ether; CCl4 / 0.08 h 3: 31 percent / NaBH4, NaHCO3 / methanol; H2O / 1.5 h / 28 °C 4: 2.) NaOH / 1.) 195-200 deg C , 45 min , 2.) H2O , EtOH , heating , 1 h View Scheme
参考文献
Bhat, K. S.; Rao, A. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 5 p. 355 - 358
反应条件
sulfuric acid T=20°C; 12 h;
参考文献
The Research Foundation of State University of New York
Patent: US7700798 B1, 2010 ;
Location in patent: Page/Page column 28 ;
