1: 2-benzoyl-propanedinitrile With phosphorus pentachloride in dichloromethane
Heating / reflux;
2: malononitrile sodium salt in ethanol
T=0°C; 24 h;
3: With hydrogenchloride in water; acetone
T=50°C; 4.5 h;
Kraybill, Brian C.; Elkin, Lisa L.; Blethrow, Justin D.; Morgan, David O.; Shokat, Kevan M.
Journal of the American Chemical Society, 2002 , vol. 124, # 41 p. 12118 - 12128