(S)-A-(氨甲基)-4-甲氧基-苯甲醇合成路线 （共 15 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; P=760 Torr; 8 h;
参考文献
Nesterenko, Vitaliy; Putt, Karson S.; Hergenrother, Paul J.
Journal of the American Chemical Society, 2003 , vol. 125, # 48 p. 14672 - 14673
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; P=760 Torr; 3 h;
参考文献
Kamal, Ahmed; Shaik, Ahmad Ali; Sandbhor, Mahendra; Malik, M. Shaheer
Tetrahedron Asymmetry, 2004 , vol. 15, # 24 p. 3939 - 3944
反应条件
hydrogen; potassium carbonate; [Rh(R,R,S,S-DuanPhos)(nbd)]SbF6 in 2,2,2-trifluoroethanol T=20°C; P=7600.51 Torr; 12 h; Title compound not separated from byproducts.;
参考文献
Shang, Gao; Liu, Duan; Allen, Scott E.; Yang, Qin; Zhang, Xumu
Chemistry - A European Journal, 2007 , vol. 13, # 27 p. 7780 - 7784
反应条件
1: sodium borohydride; activated neutral alumina / diisopropyl ether / 40 °C 2: Pseudomonas cepacia lipase immobilized on ceramic particles / diisopropyl ether / 22 h / 40 °C 3: 100 percent / anhydrous potassium carbonate / methanol / 2 h / 20 °C 4: 99 percent / hydrogen / Pd/C / methanol / 3 h / 20 °C / 760 Torr View Scheme
参考文献
Schrittwieser, Joerg H.; Coccia, Francesca; Kara, Selin; Grischek, Barbara; Kroutil, Wolfgang; D'Alessandro, Nicola; Hollmann, Frank
Green Chemistry, 2013 , vol. 15, # 12 p. 3318 - 3331
反应条件
1: Pseudomonas cepacia lipase immobilized on ceramic particles / diisopropyl ether / 22 h / 40 °C 2: 100 percent / anhydrous potassium carbonate / methanol / 2 h / 20 °C 3: 99 percent / hydrogen / Pd/C / methanol / 3 h / 20 °C / 760 Torr View Scheme
参考文献
Kamal, Ahmed; Shaik, Ahmad Ali; Sandbhor, Mahendra; Malik, M. Shaheer
Tetrahedron Asymmetry, 2004 , vol. 15, # 24 p. 3939 - 3944
反应条件
1: 100 percent / anhydrous potassium carbonate / methanol / 2 h / 20 °C 2: 99 percent / hydrogen / Pd/C / methanol / 3 h / 20 °C / 760 Torr View Scheme
参考文献
Kamal, Ahmed; Shaik, Ahmad Ali; Sandbhor, Mahendra; Malik, M. Shaheer
Tetrahedron Asymmetry, 2004 , vol. 15, # 24 p. 3939 - 3944
反应条件
1: With dimethylsulfide borane complex; C10H18BNO in tetrahydrofuran T=0°C; Reflux; 2: With hydrogenchloride; water in tetrahydrofuran T=20°C; 5 h; optical yield given as percent ee;
参考文献
Bosiak, Mariusz J.; Pakulski, Marcin M.
Synthesis, 2011 , # 2 art. no. P14610SS, p. 316 - 324
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Brussee; Dofferhoff; Kruse; Van der Gen
Tetrahedron, 1990 , vol. 46, # 5 p. 1653 - 1658
反应条件
hydrogenchloride in methanol
参考文献
Izumi, Taeko; Fukaya, Katsumi
Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 4 p. 1216 - 1221
反应条件
1: 88 percent / NaBH4 / ethanol / 6 h / 0 °C 2: 4 Angstroem sieves / hexane; tetrahydrofuran / 84 h / 25 °C / lipse from Pseudomonas cepacia 3: 10percent aq. HCl / methanol View Scheme
参考文献
Izumi, Taeko; Fukaya, Katsumi
Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 4 p. 1216 - 1221
