(1R,2R)-(-)-2-氨基-1-苯基-1,3-丙二醇合成路线 （共 20 条）
参考文献
Ogawa, Seiichiro; Mito, Tamami; Taiji, Eiichi; Jimbo, Masayuki; Yamagishi, Kiwamu; Inokuchi, Jin-Ichi
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 14 p. 1915 - 1920
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Alberti et al.
Gazzetta Chimica Italiana, 1953 , vol. 83, p. 922,924
反应条件
1: HCl 2: (S)-5-oxo-pyrrolidine-2-carboxylic acid 3: LiAlH4; diethyl ether View Scheme
参考文献
Alberti et al.
Gazzetta Chimica Italiana, 1953 , vol. 83, p. 922,924
反应条件
1: (S)-5-oxo-pyrrolidine-2-carboxylic acid 2: LiAlH4; diethyl ether View Scheme
参考文献
Alberti et al.
Gazzetta Chimica Italiana, 1953 , vol. 83, p. 922,924
参考文献
Gal; Meyer-Lehnert
Journal of pharmaceutical sciences, 1988 , vol. 77, # 12 p. 1062 - 1065
参考文献
Infinity Discovery, Inc.
Patent: US2008/114167 A1, 2008 ;
Location in patent: Page/Page column 152 ;
US 20080114167 A1
反应条件
1: 100 percent / DMAP; pyridine 2: HNO3; H2SO4 / 1.5 h / -20 - 20 °C 3: aq. HCl / 90 °C View Scheme
参考文献
Alberti et al.
Gazzetta Chimica Italiana, 1954 , vol. 84, p. 489,505
反应条件
1: 100 percent / DMAP; pyridine 2: HNO3; H2SO4 / 1.5 h / -20 - 20 °C 3: aq. HCl / 90 °C View Scheme
参考文献
Alberti et al.
Gazzetta Chimica Italiana, 1954 , vol. 84, p. 489,505
反应条件
1: 100 percent / DMAP; pyridine 2: HNO3; H2SO4 / 1.5 h / -20 - 20 °C 3: aq. HCl / 90 °C 4: 80 percent / 1 h / 90 °C View Scheme
参考文献
Boruwa, Joshodeep; Borah, Jagat C.; Gogoi, Siddhartha; Barua, Nabin C.
Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1743 - 1746
反应条件
1: 100 percent / DMAP; pyridine 2: HNO3; H2SO4 / 1.5 h / -20 - 20 °C 3: aq. HCl / 90 °C View Scheme
参考文献
Alberti et al.
Gazzetta Chimica Italiana, 1954 , vol. 84, p. 489,505
