(1R,2R)-(-)-2-氨基-1-苯基-1,3-丙二醇合成路线 （共 20 条）
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; P=760 Torr; 12 h;
参考文献
Boruwa, Joshodeep; Borah, Jagat C.; Gogoi, Siddhartha; Barua, Nabin C.
Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1743 - 1746
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; P=760 Torr; 12 h;
参考文献
Hajra, Saumen; Karmakar, Ananta; Maji, Tapan; Medda, Amiya Kumar
Tetrahedron, 2006 , vol. 62, # 38 p. 8959 - 8965
反应条件
1: chiral ferrocenylphosphine-gold(I) complex / CH2Cl2 / 20 h / 25 °C 2: conc. HCl / methanol / 3 h / 50 °C 3: LiAlH4 / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Ito, Yoshihiko; Sawamura, Masaya; Hayashi, Tamio
Journal of the American Chemical Society, 1986 , vol. 108, # 20 p. 6405 - 6406
反应条件
1: conc. HCl / methanol / 3 h / 50 °C 2: LiAlH4 / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Ito, Yoshihiko; Sawamura, Masaya; Hayashi, Tamio
Journal of the American Chemical Society, 1986 , vol. 108, # 20 p. 6405 - 6406
反应条件
1: 89 percent / NaN3 / dimethylformamide / 6 h / 25 °C 2: 90 percent / LiBH4 / tetrahydrofuran; methanol / 1 h / 0 °C 3: 99 percent / H2 / Pd/C / methanol / 12 h / 20 °C / 760 Torr View Scheme
参考文献
Hajra, Saumen; Karmakar, Ananta; Maji, Tapan; Medda, Amiya Kumar
Tetrahedron, 2006 , vol. 62, # 38 p. 8959 - 8965
反应条件
1: Ag2O; Br2 / acetone / -10 °C 2: 89 percent / NaN3 / dimethylformamide / 6 h / 25 °C 3: 90 percent / LiBH4 / tetrahydrofuran; methanol / 1 h / 0 °C 4: 99 percent / H2 / Pd/C / methanol / 12 h / 20 °C / 760 Torr View Scheme
参考文献
Hajra, Saumen; Karmakar, Ananta; Maji, Tapan; Medda, Amiya Kumar
Tetrahedron, 2006 , vol. 62, # 38 p. 8959 - 8965
反应条件
1: 90 percent / LiBH4 / tetrahydrofuran; methanol / 1 h / 0 °C 2: 99 percent / H2 / Pd/C / methanol / 12 h / 20 °C / 760 Torr View Scheme
参考文献
Hajra, Saumen; Karmakar, Ananta; Maji, Tapan; Medda, Amiya Kumar
Tetrahedron, 2006 , vol. 62, # 38 p. 8959 - 8965
反应条件
1: 89 percent / NaNO2; AcOH / H2O / 2 h / 0 - 20 °C 2: 82 percent / diphenyl phosphoryl azide; DEAD; PPh3 / tetrahydrofuran / 12 h / 0 - 20 °C 3: 97 percent / H2 / Pd/C / methanol / 12 h / 20 °C / 760 Torr View Scheme
参考文献
Boruwa, Joshodeep; Borah, Jagat C.; Gogoi, Siddhartha; Barua, Nabin C.
Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1743 - 1746
反应条件
1: 82 percent / diphenyl phosphoryl azide; DEAD; PPh3 / tetrahydrofuran / 12 h / 0 - 20 °C 2: 97 percent / H2 / Pd/C / methanol / 12 h / 20 °C / 760 Torr View Scheme
参考文献
Boruwa, Joshodeep; Borah, Jagat C.; Gogoi, Siddhartha; Barua, Nabin C.
Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1743 - 1746
参考文献
Nagawa
Takamine Kenkyusho Nenpo, 1956 , vol. 8, p. 14
Chem.Abstr., 1958 , p. 308
