二甲基吡啶-3,5-二羧酸合成路线 （共 20 条）
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride T=0°C; 3 h;
参考文献
Fuller, Anne-Marie; Leigh, David A.; Lusby, Paul J.; Oswald, Iain D. H.; Parsons, Simon; Walker, D. Barney
Angewandte Chemie - International Edition, 2004 , vol. 43, # 30 p. 3914 - 3918
反应条件
thionyl chloride; sodium chloride; sodium hydrogencarbonate in methanol
参考文献
Mochida Pharmaceutical Co., Ltd.
Patent: US6018046 A1, 2000 ;
反应条件
trifluoroacetic acid; phenol; palladium on activated charcoal T=50°C;
参考文献
Bennasar, M.-Lluisa; Zulaica, Ester; Roca, Tomas; Alonso, Yolanda; Monerris, Manuel
Tetrahedron Letters, 2003 , vol. 44, # 25 p. 4711 - 4714
反应条件
potassium carbonate in acetonitrile 3 h; Reflux;
参考文献
Patra, Ranjan; Titi, Hatem M.; Goldberg, Israel
CrystEngComm, 2013 , vol. 15, # 36 p. 7257 - 7266
反应条件
1: triethylamine / tetrahydrofuran / 0 °C 2: MeONa / tetrahydrofuran / 20 °C 3: 75 percent / phenol; TFA / 10 percent Pd/C / 50 °C View Scheme
参考文献
Bennasar, M.-Lluisa; Zulaica, Ester; Roca, Tomas; Alonso, Yolanda; Monerris, Manuel
Tetrahedron Letters, 2003 , vol. 44, # 25 p. 4711 - 4714
反应条件
1: MeONa / tetrahydrofuran / 20 °C 2: 75 percent / phenol; TFA / 10 percent Pd/C / 50 °C View Scheme
参考文献
Bennasar, M.-Lluisa; Zulaica, Ester; Roca, Tomas; Alonso, Yolanda; Monerris, Manuel
Tetrahedron Letters, 2003 , vol. 44, # 25 p. 4711 - 4714
参考文献
Banyu Pharmaceutical Co., Ltd.
Patent: US5234946 A1, 1993 ;
反应条件
in toluene Inert atmosphereReflux;
参考文献
Adkinson, Dana K.; Magri, David C.; Pitters, Jason L.; Griffiths, Keith; Norton, Peter R.; Workentin, Mark S.
Photochemistry and Photobiology, 2013 , vol. 89, # 5 p. 1020 - 1028
参考文献
Meyer,H.; Tropsch
Monatshefte fuer Chemie, 1914 , vol. 35, p. 208
参考文献
Wang, Changsheng; Jung, Gun-Young; Batsanov, Andrei S.; Bryce, Martin R.; Petty, Michael C.
Journal of Materials Chemistry, 2002 , vol. 12, # 2 p. 173 - 180
