1-(3-氨基丙基)-4-苄基哌嗪合成路线 （共 2 条）
反应条件
1: methanol / 24 h / Ambient temperature 2: H2, NH3 / Raney Ni / methanol View Scheme
参考文献
GE HEALTHCARE LIMITED; MEDI-PHYSICS, INC.; NEWINGTON, Ian, Martin; WYNN, Duncan George; NAIRNE, Robert James Domett; GUILBERT, Benedicte; MANDAL, Subrata; JINTO, Jose; VARADARAJAN, Sunderaraman; RANGASWAMY, Chitralekha; BETTS, Helen; DAVIS, Rebecca
Patent: WO2011/150183 A1, 2011 ;
WO 2011/150183 A1
反应条件
ammonia; hydrogen; nickel in methanol
参考文献
Roufos, Ioannis; Hays, Sheryl; Schwarz, Roy D.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 7 p. 1514 - 1520
