4,5-二甲基噁唑-2-胺合成路线 (共 7 条)
反应条件
1: in water T=45 - 50°C; 0.5 h; 2: With sodium hydroxide in water T=17 - 25°C; pH=10;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/99326 A1, 2007 ;
Location in patent: Page/Page column 116-117 ;
WO 2007/099326 A1
反应条件
N,N-dimethyl-formamide
参考文献
Gompper; Christmann
Chemische Berichte, 1959 , vol. 92, p. 1944,1948
反应条件
sulfuric acid Heating;
参考文献
Loop,W. et al.
Chemische Berichte, 1969 , vol. 102, # 1 p. 230 - 242
反应条件
2: iron; aqueous HCl View Scheme
参考文献
Nordmark-Werke
Patent: DE1003737 , 1957 ;
Full Text Show Details
Nordmark-Werke
Patent: US2809966 , 1956 ;
参考文献
Crank; Foulis
Journal of medicinal chemistry, 1971 , vol. 14, # 11 p. 1075 - 1077
参考文献
Crank; Foulis
Journal of medicinal chemistry, 1971 , vol. 14, # 11 p. 1075 - 1077
参考文献
Crank; Foulis
Journal of medicinal chemistry, 1971 , vol. 14, # 11 p. 1075 - 1077
Title/Abstract Full Text View citing articles Show Details
Rapi,G. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1978 , p. 249 - 252