N-苯甲酰基-2’-脱氧腺苷合成路线 （共 27 条）
反应条件
1: benzoic acid With pyridine; 4-nitro-phenol; dicyclohexyl-carbodiimide; TEA in 1,4-dioxane T=20°C; 2 h; 2: [14C]-2'-Deoxyadenosine With pyridine; dicyclohexyl-carbodiimide in 1,4-dioxane T=0°C; 2 h;
参考文献
Tripathi, Snehlata; Misra, Krishna; Sanghvi, Yogesh S.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 22 p. 5045 - 5048
反应条件
silica gel; trifluoroacetic acid in methanol; chloroform
参考文献
Pathak, Ashish K.; Pathak, Vibha; Seitz, Lainne E.; Tiwari, Kamal N.; Akhtar, Mohammad S.; Reynolds, Robert C
Tetrahedron Letters, 2001 , vol. 42, # 44 p. 7755 - 7757
反应条件
pyridine; sodium hydroxide; triethylamine 1.) RT, 1 h, 2.) THF, EtOH, 0 deg C, 15 min; Yield given. Multistep reaction;
参考文献
Xiao, Zhou; Weisz, Klaus
Journal of the American Chemical Society, 2010 , vol. 132, # 11 p. 3862 - 3869
反应条件
1: pyridine / 0.5 h / 20 °C 2: pyridine / 2 h / 20 °C 3: aq. NH4OH / 0.25 h / 20 °C View Scheme
参考文献
Grotli, Morten; Eritja, Ramon; Sproat, Brian
Tetrahedron, 1997 , vol. 53, # 33 p. 11317 - 11346
反应条件
sodium hydroxide in pyridine; methanol 0.01 h; microwave irradiation;
参考文献
Rao; Kumar; Chauhan; Garg; Gupta
Nucleosides, Nucleotides and Nucleic Acids, 2002 , vol. 21, # 4-5 p. 393 - 400
反应条件
1: pyridine / 2 h / 20 °C 2: aq. NH4OH / 0.25 h / 20 °C View Scheme
参考文献
Ti, G. S.; Gaffney, B. L.; Jones, R. A.
Journal of the American Chemical Society, 1982 , vol. 104, # 5 p. 1316 - 1319
反应条件
in benzene 1 h; Irradiation;
参考文献
Pirrung, Michael C.; Bradley, Jean-Claude
Journal of Organic Chemistry, 1995 , vol. 60, # 5 p. 1116 - 1117
反应条件
purine nucleoside phosphorylase; potassium phosphate buffer T=50°C; pH=7.0;
参考文献
Roivainen, Jarkko; Elizarova, Tatiana; Lapinjoki, Seppo; Mikhailopulo, Igor A.; Esipov, Roman S.; Miroshnikov, Anatoly I.
Nucleosides, Nucleotides and Nucleic Acids, 2007 , vol. 26, # 8-9 p. 905 - 909
反应条件
in water; acetonitrile Hydrolysis; Irradiation;
参考文献
Coleman, Michael P.; Boyd, Mary K.
Tetrahedron Letters, 1999 , vol. 40, # 45 p. 7911 - 7915
反应条件
Candida antarctica lipase B; phosphate buffer in 1,4-dioxane pH=7;
参考文献
Garcia, Javier; Fernandez, Susana; Ferrero, Miguel; Sanghvi, Yogesh S.; Gotor, Vicente
Journal of Organic Chemistry, 2002 , vol. 67, # 13 p. 4513 - 4519
