N-苯基-N-间硝基苯胺合成路线 （共 27 条）
反应条件
potassium phosphate; copper(l) iodide in N,N-dimethyl-formamide
T=110°C; Ullmann condensation; 30 h;
参考文献
Rao, Honghua; Jin, Ying; Fu, Hua; Jiang, Yuyang; Zhao, Yufen
Chemistry - A European Journal, 2006 , vol. 12, # 13 p. 3636 - 3646
反应条件
1: 3-nitro-aniline With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene
T=20°C; 0.166667 h; Inert atmosphere;
2: phenyl 1H-imidazole-1-sulfonate in toluene
T=105°C; 17 h; Inert atmosphere;
参考文献
Ackermann, Lutz; Sandmann, Rene; Song, Weifeng
Organic Letters, 2011 , vol. 13, # 7 p. 1784 - 1786
反应条件
[2,2']bipyridinyl; NiII chloride hexahydrate; 1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile
T=60°C; Chan-Lam Coupling; 28 h;
参考文献
Raghuvanshi, Dushyant Singh; Gupta, Amit Kumar; Singh, Krishna Nand
Organic Letters, 2012 , vol. 14, # 17 p. 4326 - 4329
反应条件
1: in tetrahydrofuran
T=-20°C; 2 h;
2: With sodium tetrahydroborate; iron(II) chloride in tetrahydrofuran
T=-20 - 20°C; 2 h;
参考文献
Sapountzis, Ioannis; Knochel, Paul
Synlett, 2004 , # 6 p. 955 - 958
反应条件
copper(l) iodide; potassium carbonate; 2-piperidinecarboxylic acid in N,N-dimethyl-formamide
T=110°C; Ullmann cross-coupling reaction; 36 h;
参考文献
Guo, Xun; Rao, Honghua; Fu, Hua; Jiang, Yuyang; Zhao, Yufen
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 15 p. 2197 - 2202
反应条件
1: bromobenzene With iodine; magnesium in tetrahydrofuran
Grignard reaction; Inert atmosphere;
2: With copper (I) cyanide in tetrahydrofuran
T=0°C; Inert atmosphere;
3: 1-azido-3-nitrobenzene in tetrahydrofuran
T=0°C; 2 h; Inert atmosphere;
参考文献
Yadav; Reddy, B.V. Subba; Borkar, Prashant; Reddy, P. Janardhan
Tetrahedron Letters, 2009 , vol. 50, # 48 p. 6642 - 6645
反应条件
potassium carbonate; nitrobenzene; potassium iodide
Reagens 4: Kupfer; Verseifung des entstandenen Acetylproduktes;
参考文献
Groll; Sissoeff
Chemische Berichte, 1907 , vol. 40, p. 4545
反应条件
barium dihydroxide; N-hexadecyl-N,N,N-trimethylammonium bromide in water
T=65.5°C; absence of ctab, other reagent, other solvent; Rate constantMechanism;
参考文献
Broxton, Trevor J.; Fernando, Denise R.; Rowe, Jeffrey E.
Journal of Organic Chemistry, 1981 , vol. 46, # 17 p. 3522 - 3525
反应条件
1: toluene / 5 h / |Reflux
2: sodium acetate / dichloromethane / 5 h / 20 °C / |Molecular sieve
3: dichloromethane / 6 h / 20 °C / |Molecular sieve
View Scheme
参考文献
Luo, Jun; Ji, Enwei; Ye, Jingyuan; Wu, Runze; Qiu, Lei
Tetrahedron Letters, 2013 , vol. 54, # 34 p. 4505 - 4508
反应条件
copper; potassium carbonate; potassium iodide; copper(l) chloride
参考文献
Moore; Harrington; Swingle
Journal of Medicinal Chemistry, 1975 , vol. 18, # 4 p. 386 - 391
