1,1,1-三氟-2-辛醇合成路线 （共 18 条）
参考文献
Hagiwara, Toshiki; Tanaka, Katsumi; Fuchikami, Takamasa
Tetrahedron Letters, 1996 , vol. 37, # 45 p. 8187 - 8190
反应条件
vinyl acetate in hexane; water T=50°C; Resolution of racemateEnzymatic reaction; Reagent/catalystSolventTemperature; enantioselective reaction;
参考文献
Wu, Zhuofu; Li, Wenzhao; Wang, Zhi; Qin, Ling; Liu, Yunling; Huo, Qisheng; Li, Zhengqiang
RSC Advances, 2014 , vol. 4, # 12 p. 6103 - 6109
反应条件
2-(N,N-dimethylamino)-pyridine; triethylamine in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane
参考文献
Showa Shell Sekiyu Kabushiki Kaisha
Patent: US5207947 A1, 1993 ;
反应条件
vinyl acetate in hexane; water T=50°C; Resolution of racemateEnzymatic reaction; Reagent/catalystSolventTemperature; enantioselective reaction;
参考文献
Wu, Zhuofu; Li, Wenzhao; Wang, Zhi; Qin, Ling; Liu, Yunling; Huo, Qisheng; Li, Zhengqiang
RSC Advances, 2014 , vol. 4, # 12 p. 6103 - 6109
反应条件
1: pyridine / diethyl ether; benzene 2: water; Candida rugosa lipase / 12 h / 38 °C / pH 7.28 / aq. phosphate buffer; Enzymatic reaction View Scheme
参考文献
Pozhidaev; Torgova; Molkin; Minchenko; Vashchenko; Krivoshey; Strigazzi
Molecular Crystals and Liquid Crystals, 2009 , vol. 509, # 1 p. 300 - 308
反应条件
triethylamine in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane
反应条件
2-(N,N-dimethylamino)-pyridine; triethylamine in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane
反应条件
triethylamine in dichloromethane
反应条件
1-tert-butyl-4,4,4-tris(dimethylamino)-2,2-bis[tris(dimethylamino)-phosphoranylidenamino]-2Λ54Λ5-catenadi(phosphazene) in tetrahydrofuran; hexane
T=-40°C; 3 h; Inert atmosphere;
参考文献
Zhang, Yuan; Fujiu, Motohiro; Serizawa, Hiroki; Mikami, Koichi
Journal of Fluorine Chemistry, 2013 , vol. 156, p. 367 - 371
反应条件
tetrabutylammomium bromide in N,N-dimethyl-formamide
T=-10°C; 5 h; zinc rod anode, nickel cathode, 0.3 A;
参考文献
Sibille, S.; Mcharek, S.; Perichon, J.
Tetrahedron, 1989 , vol. 45, # 5 p. 1423 - 1428
