5-(5-氟-2-氧代-1,2-二氢-吲哚-3-亚基甲基)-2,4-二甲基-1H-吡咯-3-羧酸合成路线 (共 4 条)
反应条件
pyrrolidine in ethanol 3 h; Reflux;
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 52, # 9 p. 360 - 365
反应条件
1.1: trichlorophosphate / dichloromethane / 1.25 h / 4 °C / Reflux 1.2: 10 °C 2.1: potassium hydroxide / water / 5 h / Reflux 2.2: pH 4 3.1: pyrrolidine / ethanol / 3 h / Reflux View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 52, # 9 p. 360 - 365
反应条件
1: hydrazine hydrate; triethylamine / butan-1-ol / 15.5 h / 20 - 100 °C 2: pyrrolidine / ethanol / 3 h / Reflux View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 52, # 9 p. 360 - 365
反应条件
1.1: potassium hydroxide / water / 5 h / Reflux 1.2: pH 4 2.1: pyrrolidine / ethanol / 3 h / Reflux View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 52, # 9 p. 360 - 365