1: 66 percent / AlCl3 / 1,2-dichloro-ethane / 20 h / 25 °C
2: 34 percent / Et3N / dimethylformamide / 3 h / 40 - 50 °C
View Scheme
参考文献
Woltersdorf, O. W.; Schwam, H.; Bicking, J. B.; Brown, S. L.; deSolms, S. J.; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 11 p. 2486 - 2492
1: 66 percent / AlCl3 / 1,2-dichloro-ethane / 20 h / 25 °C
2: 21 percent / Et3N / dimethylformamide / 3 h / 40 - 50 °C
View Scheme
参考文献
Woltersdorf, O. W.; Schwam, H.; Bicking, J. B.; Brown, S. L.; deSolms, S. J.; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 11 p. 2486 - 2492
1: 66 percent / AlCl3 / 1,2-dichloro-ethane / 20 h / 25 °C
2: 18 percent / pyridine, 4-(dimethylamino)pyridine / 1.5 h / 25 °C
View Scheme
参考文献
Woltersdorf, O. W.; Schwam, H.; Bicking, J. B.; Brown, S. L.; deSolms, S. J.; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 11 p. 2486 - 2492
