1,1,3-三甲基环戊烷合成路线 （共 79 条）
反应条件
1: 1) Mg / THF 2: LiAlH4 / diethyl ether / 0 °C 3: 6.6 g / Br2 / PPh3 / pyridine / 20 h / Heating 4: 7.5 percent Chromat. / LiAlH4 / tetrahydrofuran / 480 h / Ambient temperature View Scheme
参考文献
Ashby, E. C.; DePriest, R. N.; Goel, A. B.; Wenderoth, Bernd; Pham, Tung N.
Journal of Organic Chemistry, 1984 , vol. 49, # 19 p. 3545 - 3556
反应条件
1: LiAlH4 / diethyl ether / 0 °C 2: 6.6 g / Br2 / PPh3 / pyridine / 20 h / Heating 3: 7.5 percent Chromat. / LiAlH4 / tetrahydrofuran / 480 h / Ambient temperature View Scheme
参考文献
Ashby, E. C.; DePriest, R. N.; Goel, A. B.; Wenderoth, Bernd; Pham, Tung N.
Journal of Organic Chemistry, 1984 , vol. 49, # 19 p. 3545 - 3556
反应条件
in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=24°C; 60 h; Title compound not separated from byproducts;
参考文献
Ashby, E.C.; Argyropoulos, J.N.
Tetrahedron Letters, 1984 , vol. 25, # 1 p. 7 - 10
反应条件
1: I2, Et3N / diethyl ether 2: 7 percent Chromat. / LiAlH4 / tetrahydrofuran / 21 h / 25 °C View Scheme
参考文献
Ashby, E. C.; Deshpande, Abhay K.
Journal of Organic Chemistry, 1994 , vol. 59, # 14 p. 3798 - 3805
反应条件
1: 60 percent / hexaphenylditin / benzene / 15 h / Heating 2: LDA / tetrahydrofuran / 48 h / 0 °C View Scheme
参考文献
Ashby, E. C.; Park, B.; Patil, G. S.; Gadru, K.; Gurumurthy, R.
Journal of Organic Chemistry, 1993 , vol. 58, p. 424 - 437
反应条件
dicyclo-hexylphosphine in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=24°C; 4 h; Further byproducts given. Title compound not separated from byproducts;
参考文献
Ashby, E.C.; Argyropoulos, J.N.
Tetrahedron Letters, 1984 , vol. 25, # 1 p. 7 - 10
反应条件
platinum on activated charcoal T=310°C;
参考文献
Liberman et al.
Doklady Akademii Nauk SSSR, 1959 , vol. 129, p. 578
Pr. Akad. Sci. U.S.S.R. Chem. Sect., 124-129 <1959> 1027
Full Text Show Details
Kasanskii et al.
Doklady Chemistry, 124-129 <1959> 891
Full Text Show Details
Kasanskii et al.
Doklady Akademii Nauk SSSR, 1954 , vol. 95, p. 281
Doklady Akademii Nauk SSSR, 1959 , vol. 128, p. 1188
Chem.Abstr., 1955 , p. 3834
反应条件
in tetrahydrofuran T=25°C; 0.5 h; Title compound not separated from byproducts;
参考文献
Ashby, E. C.; Gurumurthy, R.; Ridlehuber, R. W.
Journal of Organic Chemistry, 1993 , vol. 58, # 21 p. 5832 - 5837
反应条件
ethylmagnesium bromide; acetone 1.) ether, 3 days, 2.) ether, 1 h; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given;
参考文献
Ashby, E. C.; Bowers, Joseph R.
Journal of the American Chemical Society, 1981 , vol. 103, # 9 p. 2242 - 2250
反应条件
lithium triethylborohydride in tetrahydrofuran T=24°C; 24 h;
参考文献
Ashby, Eugene C.; DePriest, Robert N.; Goel, Anil B.
Tetrahedron Letters, 1981 , vol. 22, # 19 p. 1763 - 1766
