1: 89 percent / LiHMDS; PPh3; [Ni(cod)2] / tetrahydrofuran; hexane / 1 h 2: 78 percent / ceric ammonium nitrate / acetonitrile; H2O 3: 88 percent / triethylamine / CH2Cl2 4: 88 percent / Cs2CO3 / methanol View Scheme

1: 89 percent / LiHMDS; PPh3; [Ni(cod)2] / tetrahydrofuran; hexane / 1 h 2: 78 percent / ceric ammonium nitrate / acetonitrile; H2O 3: 88 percent / triethylamine / CH2Cl2 4: 88 percent / Cs2CO3 / methanol 5: 82 percent / CrO3; H2SO4 / H2O; acetone View Scheme

bis(1,5-cyclooctadiene)nickel (0); triphenylphosphine; lithium hexamethyldisilazane in tetrahydrofuran; hexane 1 h;

1: 64 percent / (R)-MeO-BIPHEP / Ni(cod)2 / tetrahydrofuran / 6 h / 20 °C 2: 75 percent / CAN / acetonitrile; H2O / 0.5 h / 0 °C 3: 84 percent / Et3N / CH2Cl2 / 60 h / 20 °C 4: 77 percent / Cs2CO3 / methanol / 1.5 h View Scheme